Table 5

Multivariate analysis of baseline parameters and pretransplantation percentage SFLC reduction associated with event-free and overall survival

Variablen/N (%)HR (95% CI)P
Overall survival from transplantation 1    
    Top-tertile % SFLC reduction, before transplantation 93/279 (33) 2.24 (1.03-4.87) .042 
    LDH of 190 U/L or higher 70/279 (25) 2.58 (1.18-5.65) .018 
    CAs 92/279 (33) 2.90 (1.34-6.27) .007 
Event-free survival from transplantation 1    
    Top-tertile % SFLC reduction, before transplantation 93/279 (33) 2.01 (1.02-3.97) .045 
    LDH of 190 U/L or higher 70/279 (25) 2.12 (1.06-4.24) .034 
    CAs 92/279 (33) 2.52 (1.30-4.91) .007 
Variablen/N (%)HR (95% CI)P
Overall survival from transplantation 1    
    Top-tertile % SFLC reduction, before transplantation 93/279 (33) 2.24 (1.03-4.87) .042 
    LDH of 190 U/L or higher 70/279 (25) 2.58 (1.18-5.65) .018 
    CAs 92/279 (33) 2.90 (1.34-6.27) .007 
Event-free survival from transplantation 1    
    Top-tertile % SFLC reduction, before transplantation 93/279 (33) 2.01 (1.02-3.97) .045 
    LDH of 190 U/L or higher 70/279 (25) 2.12 (1.06-4.24) .034 
    CAs 92/279 (33) 2.52 (1.30-4.91) .007 

P value from Wald chi-square test in Cox regression analysis. Multivariate model uses stepwise selection with entry level .1 and variable remains if meets the .05 level.

HR indicates hazard ratio; 95% CI, 95% confidence interval.

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