Multivariate analysis of variables associated with near-complete response
| Variable . | N . | With factor (%) . | Without factor (%) . | OR (95% CI) . | P . |
|---|---|---|---|---|---|
| Including “disease type” variables* | |||||
| Non-IgG Isotype | 297 | 63/125 (50) | 13/172 (8) | 8.90 (4.30-18.38) | < .001 |
| Light-chain only | 297 | 31/49 (63) | 45/248 (18) | 2.37 (1.13-4.95) | .022 |
| Excluding “disease type” variables* | |||||
| Baseline SFLC higher than 75 mg/dL | 301 | 37/100 (37) | 41/201 (20) | 1.99 (1.15-3.44) | .014 |
| LDH of 190 U/L or more | 301 | 31/80 (39) | 47/221 (21) | 2.00 (1.13-3.55) | .017 |
| Variable . | N . | With factor (%) . | Without factor (%) . | OR (95% CI) . | P . |
|---|---|---|---|---|---|
| Including “disease type” variables* | |||||
| Non-IgG Isotype | 297 | 63/125 (50) | 13/172 (8) | 8.90 (4.30-18.38) | < .001 |
| Light-chain only | 297 | 31/49 (63) | 45/248 (18) | 2.37 (1.13-4.95) | .022 |
| Excluding “disease type” variables* | |||||
| Baseline SFLC higher than 75 mg/dL | 301 | 37/100 (37) | 41/201 (20) | 1.99 (1.15-3.44) | .014 |
| LDH of 190 U/L or more | 301 | 31/80 (39) | 47/221 (21) | 2.00 (1.13-3.55) | .017 |
P value from Wald chi-square test in logistic regression.
Multivariate model uses stepwise selection with entry level .1 and variable remains if meets the .05 level.
Multivariate model considered the following factors for stepwise regression: female sex, age of 65 years or older, albumin less than 3.5 g/dL, LDH of 190 U/L or higher, and baseline SFLC higher than 75 mg/dL.
OR indicates odds ratio; 95% CI, 95% confidence interval.
“Disease type” variables are IgG isotype, IgA isotype, and light-chain only.