Characteristics of 32 primary infection episodes (in 30 subjects) attributable to respiratory viruses after HCT
| Virus . | No. of infection episodes . | Days to positive test, median (range) . | Days of viral shedding, median (range)* . | No. of infection episodes by diagnostic method . | No. of infection episodes with symptoms . | ||||
|---|---|---|---|---|---|---|---|---|---|
| RT-PCR . | RT-PCR + DFA/culture . | DFA/culture . | Asymptomatic . | LRI . | URI . | ||||
| RSV | 6 | 52 (5-72) | 16 (5-39) | 1 | 5 | 0 | 0 | 1 | 5 |
| PIV | 17 | 47 (12-96) | 11 (6-42) | 8 | 6 | 3† | 6 | 2 | 9 |
| MPV | 6 | 57 (3-79) | 16 (7-24) | 6 | — | — | 0 | 0 | 6 |
| Influenza | 4 | 44 (3-69) | 14 (7-24) | 0 | 4 | 0 | 0 | 0 | 4 |
| Total | 32‡ | 49 (3-96) | 14 (5-42) | 15 | 15 | 3 | 6 | 3 | 23 |
| Virus . | No. of infection episodes . | Days to positive test, median (range) . | Days of viral shedding, median (range)* . | No. of infection episodes by diagnostic method . | No. of infection episodes with symptoms . | ||||
|---|---|---|---|---|---|---|---|---|---|
| RT-PCR . | RT-PCR + DFA/culture . | DFA/culture . | Asymptomatic . | LRI . | URI . | ||||
| RSV | 6 | 52 (5-72) | 16 (5-39) | 1 | 5 | 0 | 0 | 1 | 5 |
| PIV | 17 | 47 (12-96) | 11 (6-42) | 8 | 6 | 3† | 6 | 2 | 9 |
| MPV | 6 | 57 (3-79) | 16 (7-24) | 6 | — | — | 0 | 0 | 6 |
| Influenza | 4 | 44 (3-69) | 14 (7-24) | 0 | 4 | 0 | 0 | 0 | 4 |
| Total | 32‡ | 49 (3-96) | 14 (5-42) | 15 | 15 | 3 | 6 | 3 | 23 |
— indicates not done.
Follow-up specimens were available for analysis in 19 of the 32 total infection episodes.
Three PIV infections were detected only by conventional testing; 2 of 3 subjects had samples sent for clinical testing that were unavailable to be tested by RT-PCR. The third subject's respiratory sample was tested by RT-PCR and culture and found to be positive by culture alone.
There was one influenza B/RSV coinfection; therefore, the column total is 32 instead of 33.