Characteristics of 6 patients with PIV asymptomatic respiratory virus infection episodes after HCT
| Patient no. . | No. of positive respiratory samples (virus) . | Age, y . | Sex . | Primary diagnosis . | Primary disease status . | HCT month/year . | HCT donor type . | Cell source . | Transplant no. . | Myeloablative . | Days to neutrophil engraftment after HCT . | Days to viral detection after HCT . | Detection method . | Symptom follow-up (chart review) . |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | 1 (PIV1) | 38 | M | ALL | Remission | April 2001 | Syn | PBSCs | 1 | No | 11 | 41 | PCR | Runny nose noted 1 wk before, no symptoms at or after PIV-positive test |
| 2 | 1 (PIV1) | 57 | M | AML | Relapse | May 2003 | Allo | PBSCs | 1 | No | 17 | 33 | PCR | No symptoms noted |
| 3 | 1 (PIV3) | 48 | M | NHL | Remission | May 2003 | Allo | PBSCs | 2 | Yes | 16 | 96 | PCR | No symptoms noted |
| 4 | 1 (PIV3) | 50 | F | AML | Remission | April 2003 | Allo | PBSCs | 1 | No | 17 | 90 | PCR and culture | 6 d after positive PIV test: runny nose, sneezing, cough, wheeze (noted as allergies in chart) |
| 5 | 1 (PIV3) | 55 | M | CML | Blast crisis | May 2004 | Allo | PBSCs | 1 | No | 13 | 76 | PCR | No symptoms noted |
| 6 | 2 (PIV1) | 26 | M | CML | Accelerated phase | May–June 2003 | Allo | PBSCs | 1 | No | 16 | 40 | Culture | No symptoms noted |
| Patient no. . | No. of positive respiratory samples (virus) . | Age, y . | Sex . | Primary diagnosis . | Primary disease status . | HCT month/year . | HCT donor type . | Cell source . | Transplant no. . | Myeloablative . | Days to neutrophil engraftment after HCT . | Days to viral detection after HCT . | Detection method . | Symptom follow-up (chart review) . |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | 1 (PIV1) | 38 | M | ALL | Remission | April 2001 | Syn | PBSCs | 1 | No | 11 | 41 | PCR | Runny nose noted 1 wk before, no symptoms at or after PIV-positive test |
| 2 | 1 (PIV1) | 57 | M | AML | Relapse | May 2003 | Allo | PBSCs | 1 | No | 17 | 33 | PCR | No symptoms noted |
| 3 | 1 (PIV3) | 48 | M | NHL | Remission | May 2003 | Allo | PBSCs | 2 | Yes | 16 | 96 | PCR | No symptoms noted |
| 4 | 1 (PIV3) | 50 | F | AML | Remission | April 2003 | Allo | PBSCs | 1 | No | 17 | 90 | PCR and culture | 6 d after positive PIV test: runny nose, sneezing, cough, wheeze (noted as allergies in chart) |
| 5 | 1 (PIV3) | 55 | M | CML | Blast crisis | May 2004 | Allo | PBSCs | 1 | No | 13 | 76 | PCR | No symptoms noted |
| 6 | 2 (PIV1) | 26 | M | CML | Accelerated phase | May–June 2003 | Allo | PBSCs | 1 | No | 16 | 40 | Culture | No symptoms noted |
ALL indicates acute lymphocytic leukemia; AML, acute myeloid leukemia; NHL, non-Hodgkin lymphoma; CML, chronic myeloid leukemia; Syn, Syngeneic; Allo, Allogeneic; PBSCs, peripheral blood stem cells.