Table 1

The percentages of protein secretion (medium/cells + medium), the estimated concentrations of the proteins in the culture media, and the VWF-cleaving activity levels of the secreted proteins

ProteinSecretion, % (n)Medium, nM (n)Activity, U/nmol* (n)
Full-length 23 ± 7 (5) 1.6 ± 0.4 (4) 578 ± 72 (3) 
IAP-a 33 ± 12 (5) 6.7 ± 1.6 (4) 65 ± 16 (4) 
IAP-b 5 ± 1 (3) 2 ± 0.9 (3) <0.05 U 
ProteinSecretion, % (n)Medium, nM (n)Activity, U/nmol* (n)
Full-length 23 ± 7 (5) 1.6 ± 0.4 (4) 578 ± 72 (3) 
IAP-a 33 ± 12 (5) 6.7 ± 1.6 (4) 65 ± 16 (4) 
IAP-b 5 ± 1 (3) 2 ± 0.9 (3) <0.05 U 

All values are expressed as mean ± SD. The numbers (n) of expressed proteins analyzed are also indicated for each cDNA.

*

Measured against VWF multimers as the substrate.

P < .01 (compared with full-length values).

P < .05.

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