Table 6

Differential expression between IF patients and drug-resistant cell lines identified 7 up-regulated genes

Affymetrix codeDrugGene nameDescriptionGO functionLocus
216203_at DNR SPTLC2 Serine palmitoyltransferase, long chain base subunit 2 Biosynthesis 14q24.3-q31 
218618_s_at DNR FAD104 FAD104 Hematopoietin/interferon class 3q26.31 
*223380_s_at *227013_at DNR LATS2 LATS, large tumor suppressor, homolog 2 (DrosophilaProtein serine/threonine kinase activity 13q11-q12 
207761_s-at DNR DKFZ P586A0522 — S-adenosylmethionine-dependent methyltransferase activity 12q13.13 
226550_at DNR, ASP — FLJ39602 — Xp11.3 
218847_at ASP IMP2 IGF-II mRNA-binding protein 2 Translational attenuation; morphogenesis; RNA binding 3q28 
235824_at ASP EST Homo sapiens transcribed sequences — — 
Affymetrix codeDrugGene nameDescriptionGO functionLocus
216203_at DNR SPTLC2 Serine palmitoyltransferase, long chain base subunit 2 Biosynthesis 14q24.3-q31 
218618_s_at DNR FAD104 FAD104 Hematopoietin/interferon class 3q26.31 
*223380_s_at *227013_at DNR LATS2 LATS, large tumor suppressor, homolog 2 (DrosophilaProtein serine/threonine kinase activity 13q11-q12 
207761_s-at DNR DKFZ P586A0522 — S-adenosylmethionine-dependent methyltransferase activity 12q13.13 
226550_at DNR, ASP — FLJ39602 — Xp11.3 
218847_at ASP IMP2 IGF-II mRNA-binding protein 2 Translational attenuation; morphogenesis; RNA binding 3q28 
235824_at ASP EST Homo sapiens transcribed sequences — — 

— indicates not applicable.

*

Shared probesets for LATS2.

Probeset shared between DNR and ASP-resistant cell lines.

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