Dose, duration, and response to imatinib and the results of the recent follow-up
Pt . | Imatinib dose . | Response to imatinib . | Duration of therapy, mo . | Current status . | Most recent WBC, × 109/L . | Most recent Eos, × 109/L . | Most recent Plts, × 109/L . | Most recent cytogenetics and/or FISH (mo after imatinib start) . | Duration of survival since diagnosis, mo . |
---|---|---|---|---|---|---|---|---|---|
1 | 400 | Yes | 60 | Alive | 5.6 | 0.2 | 224 | Normal (24) | 75 |
2 | 300 | Yes | 55 | Alive | 5.8 | 0.1 | 235 | Normal (24) | 73 |
3 | 400 | Yes | 55 | Alive | 4.6 | 0.28 | 166 | Normal (51) | 109 |
4 | 400 | Yes | 48 | Alive | 9.4 | 0.09 | 303 | Normal (39) | 57 |
5 | 400 | Yes | 46 | Alive | 5.7 | 0.6 | 232 | Normal (12) | 55 |
6 | 400 | Yes | 46 | Alive | 4.6 | 0.3 | 150 | Normal (41) | 47 |
7 | 400 | Yes | 33 | Alive | 4.9 | 0.08 | 231 | Normal (24) | 34 |
8 | 400 | Yes | 19 | Alive | 4.3 | 0.29 | 196 | Normal (16) | 36 |
9 | 800 | Yes | 60 | Alive | 5.5 | 0.6 | 324 | Normal (60) | 234 |
10 | 200 | Yes | 50 | Alive | 6.3 | 0.1 | 296 | Normal (30) | 75 |
11 | 400 | Yes; PR | 8 | Dead | NA | NA | NA | NA | 25 (dead) |
12 | 400 | Yes* | 0.1 | Dead | NA | NA | NA | NA | 91 (dead) |
Pt . | Imatinib dose . | Response to imatinib . | Duration of therapy, mo . | Current status . | Most recent WBC, × 109/L . | Most recent Eos, × 109/L . | Most recent Plts, × 109/L . | Most recent cytogenetics and/or FISH (mo after imatinib start) . | Duration of survival since diagnosis, mo . |
---|---|---|---|---|---|---|---|---|---|
1 | 400 | Yes | 60 | Alive | 5.6 | 0.2 | 224 | Normal (24) | 75 |
2 | 300 | Yes | 55 | Alive | 5.8 | 0.1 | 235 | Normal (24) | 73 |
3 | 400 | Yes | 55 | Alive | 4.6 | 0.28 | 166 | Normal (51) | 109 |
4 | 400 | Yes | 48 | Alive | 9.4 | 0.09 | 303 | Normal (39) | 57 |
5 | 400 | Yes | 46 | Alive | 5.7 | 0.6 | 232 | Normal (12) | 55 |
6 | 400 | Yes | 46 | Alive | 4.6 | 0.3 | 150 | Normal (41) | 47 |
7 | 400 | Yes | 33 | Alive | 4.9 | 0.08 | 231 | Normal (24) | 34 |
8 | 400 | Yes | 19 | Alive | 4.3 | 0.29 | 196 | Normal (16) | 36 |
9 | 800 | Yes | 60 | Alive | 5.5 | 0.6 | 324 | Normal (60) | 234 |
10 | 200 | Yes | 50 | Alive | 6.3 | 0.1 | 296 | Normal (30) | 75 |
11 | 400 | Yes; PR | 8 | Dead | NA | NA | NA | NA | 25 (dead) |
12 | 400 | Yes* | 0.1 | Dead | NA | NA | NA | NA | 91 (dead) |
FISH indicates fluorescence in situ hybridization; NA, not applicable.
Disease response without recovery of peripheral-blood counts; see the fourth paragraph of “Results and discussion.”