Updated results on previously published patients
| Ref . | Age at diagnosis, y . | Sex, M/F . | Duration of disease, mo . | Cytogenetics . | Fusion gene . | Time to CHR, mo . | Duration of follow-up at time of paper/now, mo . | Best response in paper . | Current status . | Most recent cytogenetics/FISH (time since treatment, mo) . | Most recent RT-PCR . |
|---|---|---|---|---|---|---|---|---|---|---|---|
| 5 | 29 | M | Relapse after BMT | t(5;17) | RAB5EP-PDGFRB | Treated in MolR after BMT | 6/36 | MolR; 6 wk | Alive, off treatment 4 months | CCyR (46) | Neg to 28 mo |
| 6 | 44 | M | 17 | t(5;10) | H4-PDGFRB | 0.75 | 12/34 | CCyR; 3 wk | Alive | CCyR (32) | ND |
| 7 | 68 | M | 1 | t(5,12) | ETV6-PDGFRB | 0.75 | 10/38 | CCyR; 4 mo | Alive | CCyR (37) | ND |
| 8 | 1 | F | 12 | t(1;5) | Myomegalin-PDGFRB | <1 | 7/36 | PCyR | Alive CHR | 7% t(1;5) by FISH (6) | NA |
| 9 | 49 | M | 29 | t(5;10) | H4-PDGFRB | NA | 6/6 | No response | Alive; CHR on HU | NA | NA |
| 10 | 2 | F | 9 | t(5;12) (q33;p13) | ETV6-PDGFRB | 1 | BMT | CCyR; 4 mo | Died; GvHD | NA | NA |
| 11 | 35 | M | 150 | t(5;14) | NIN-PDGFRB | 18/36 | CCyR; 11 mo | Alive | CCyR (36) | Pos at 38 mo | |
| 12 | 42 | M | 3 | t(5;14) | PDGFRB-KIAA1509 | 1 | 18/32 | CCyR; 3 mo | Alive | CCyR (31) | ND |
| Ref . | Age at diagnosis, y . | Sex, M/F . | Duration of disease, mo . | Cytogenetics . | Fusion gene . | Time to CHR, mo . | Duration of follow-up at time of paper/now, mo . | Best response in paper . | Current status . | Most recent cytogenetics/FISH (time since treatment, mo) . | Most recent RT-PCR . |
|---|---|---|---|---|---|---|---|---|---|---|---|
| 5 | 29 | M | Relapse after BMT | t(5;17) | RAB5EP-PDGFRB | Treated in MolR after BMT | 6/36 | MolR; 6 wk | Alive, off treatment 4 months | CCyR (46) | Neg to 28 mo |
| 6 | 44 | M | 17 | t(5;10) | H4-PDGFRB | 0.75 | 12/34 | CCyR; 3 wk | Alive | CCyR (32) | ND |
| 7 | 68 | M | 1 | t(5,12) | ETV6-PDGFRB | 0.75 | 10/38 | CCyR; 4 mo | Alive | CCyR (37) | ND |
| 8 | 1 | F | 12 | t(1;5) | Myomegalin-PDGFRB | <1 | 7/36 | PCyR | Alive CHR | 7% t(1;5) by FISH (6) | NA |
| 9 | 49 | M | 29 | t(5;10) | H4-PDGFRB | NA | 6/6 | No response | Alive; CHR on HU | NA | NA |
| 10 | 2 | F | 9 | t(5;12) (q33;p13) | ETV6-PDGFRB | 1 | BMT | CCyR; 4 mo | Died; GvHD | NA | NA |
| 11 | 35 | M | 150 | t(5;14) | NIN-PDGFRB | 18/36 | CCyR; 11 mo | Alive | CCyR (36) | Pos at 38 mo | |
| 12 | 42 | M | 3 | t(5;14) | PDGFRB-KIAA1509 | 1 | 18/32 | CCyR; 3 mo | Alive | CCyR (31) | ND |
Ref indicates reference; M, male; BMT, bone marrow transplantation; MolR, molecular response; CCyR, complete cytogenetic remission; neg, negative; ND, not done; F, female; PCyR, partial cytogenetic remission; CHR, complete hematologic remission; NA, not applicable; HU, hydroxyurea; GvHD, graft-versus-host disease; and pos, positive.