Table 1

A comparative analysis of cytokines released by LPS-activated M-DCs and TGF-M-DCs

Cytokines, pg/mL
CM: mature (LPS-stimulated) M-DCsCM: mature (LPS-stimulated) TGF-M-DCs
Significant decrease from M-DCs to TGF-M-DCs   
    IL-1β 17 ± 2 ND* 
    IL-6 12804 ± 3186 4092 ± 987* 
    IL-10 3798 ± 736 1218 ± 415* 
    GM-CSF 179 ± 10 58 ± 9* 
    VEGF 588 ± 232 82 ± 25 
No change from M-DCs to TGF-M-DCs   
    SDF-1α 750 ± 543 325 ± 192 
    TGFβ 13 ± 8 5 ± 3 
    TPO ND 7687 ± 6556 
    PDGF-BB 200 ± 78 374 ± 87 
    IL-2 7 ± 1 7 ± 1 
    M-CSF ND 2 ± 2 
    IL-3 ND ND 
    IL-12 ND ND 
    IL-17 ND ND 
Cytokines, pg/mL
CM: mature (LPS-stimulated) M-DCsCM: mature (LPS-stimulated) TGF-M-DCs
Significant decrease from M-DCs to TGF-M-DCs   
    IL-1β 17 ± 2 ND* 
    IL-6 12804 ± 3186 4092 ± 987* 
    IL-10 3798 ± 736 1218 ± 415* 
    GM-CSF 179 ± 10 58 ± 9* 
    VEGF 588 ± 232 82 ± 25 
No change from M-DCs to TGF-M-DCs   
    SDF-1α 750 ± 543 325 ± 192 
    TGFβ 13 ± 8 5 ± 3 
    TPO ND 7687 ± 6556 
    PDGF-BB 200 ± 78 374 ± 87 
    IL-2 7 ± 1 7 ± 1 
    M-CSF ND 2 ± 2 
    IL-3 ND ND 
    IL-12 ND ND 
    IL-17 ND ND 

ND indicates nondetectable in all 4 donor samples.

*

P < .05 when using 2-tailed t test.

P < .05 when using 1-tailed t test.

Close Modal

or Create an Account

Close Modal
Close Modal