Table 2 Proliferative rate of different... | American Society of Hematology

Table 2

Proliferative rate of different maturation-associated B-cell compartments from normal adult bone marrow (BM), peripheral blood (PB), and reactive lymph node (RLN) samples

Type of sample/ B-cell compartment	Proliferative rate (% of S+G2/M cells)	P
BM		<.001*
CD45^lo/CD19^lo	7 ± 2.4
CD45⁺/CD19^hi	3 ± 1.2
CD45^hi/CD19⁺	0.5 ± 1.1
CD38^hi/CD19^−/+	3 ± 1.1
PB		NS
CD20⁺/CD23⁺	0.1 ± 0.8
CD20⁺/CD23⁻	0.1 ± 0.05
RLN		<.05†
CD38^lo/CD20⁺	2 ± 3
CD38⁺/CD20^hi	13.5 ± 8
CD38^hi/CD20^−/lo	5.4 ± 2

Type of sample/ B-cell compartment	Proliferative rate (% of S+G2/M cells)	P
BM		<.001*
CD45^lo/CD19^lo	7 ± 2.4
CD45⁺/CD19^hi	3 ± 1.2
CD45^hi/CD19⁺	0.5 ± 1.1
CD38^hi/CD19^−/+	3 ± 1.1
PB		NS
CD20⁺/CD23⁺	0.1 ± 0.8
CD20⁺/CD23⁻	0.1 ± 0.05
RLN		<.05†
CD38^lo/CD20⁺	2 ± 3
CD38⁺/CD20^hi	13.5 ± 8
CD38^hi/CD20^−/lo	5.4 ± 2

Results are expressed as means plus or minus 1 standard deviation (range).

NS indicates no statistically significant differences: P > .05.

P < .001 for all BM B-cell compartments versus CD45^loCD19^lo B-cell precursors.

†

P < .05 for all LN B-cell compartments versus CD38⁺CD20^hi B lymphocytes.

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