Table 2

Findings at diagnosis and during the course of TL significantly associated with a higher cumulative incidence of death (CID)

VariableCID at 5 y, %
PGray
YesNo
At diagnosis    
    High WBC count (> 100 ×109/L) 38 ± 11 12 ± 3 .002 
    Hydrops fetalis 71 ± 17 12 ± 3 < .001 
    Ascites 58 ± 14 11 ± 3 < .001 
    Effusions (pleural, pericardial, ascites, or hydrops) 30 ± 8 11 ± 3 .008 
    Coagulopathy 39 ± 10 11 ± 3 < .001 
    Bleeding diatheses 67 ± 16 12 ± 3 < .001 
    Platelet levels > 100 × 109/L 21 ± 5 6 ± 3 .023 
    Preterm delivery 35 ± 8 8 ± 4 .002 
    Birth weight less than 3 kg 33 ± 9 14 ± 4 .021 
During course of disease    
    Cholestasis 38 ± 12 12 ± 3 .007 
    Liver fibrosis 100 ± 13 12 ± 3 < .001 
    Liver dysfunction 31 ± 8 11 ± 3 .003 
    Renal failure 100 11 ± 3 < .001 
VariableCID at 5 y, %
PGray
YesNo
At diagnosis    
    High WBC count (> 100 ×109/L) 38 ± 11 12 ± 3 .002 
    Hydrops fetalis 71 ± 17 12 ± 3 < .001 
    Ascites 58 ± 14 11 ± 3 < .001 
    Effusions (pleural, pericardial, ascites, or hydrops) 30 ± 8 11 ± 3 .008 
    Coagulopathy 39 ± 10 11 ± 3 < .001 
    Bleeding diatheses 67 ± 16 12 ± 3 < .001 
    Platelet levels > 100 × 109/L 21 ± 5 6 ± 3 .023 
    Preterm delivery 35 ± 8 8 ± 4 .002 
    Birth weight less than 3 kg 33 ± 9 14 ± 4 .021 
During course of disease    
    Cholestasis 38 ± 12 12 ± 3 .007 
    Liver fibrosis 100 ± 13 12 ± 3 < .001 
    Liver dysfunction 31 ± 8 11 ± 3 .003 
    Renal failure 100 11 ± 3 < .001 
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