Table 3 In vitro characterization of... | American Society of Hematology

Table 3

In vitro characterization of galactosylated and control (unmodified) human platelets after storage for 48 hours at 4°C or 22°C

	UDP-galactose–treated, 4°C-stored*				Control 4°C-stored†		Control 22°-stored†		Normal range
	Vol 1	Vol 2	Vol 3	Vol 4	Vol 1	Vol 3	Vol 2	Vol 4	Normal range
Platelet count, × 10¹¹	1.75	1.97	1.69	1.88	1.74	1.81	2.19	1.89	—
pH	7.3	7.2	7.2	7.2	7.3	7.2	7.3	7.3	6.4-7.2
pCO₂, mmHg	29	29	36	26	31	28	23	15	9.0-47.0
pO₂, mmHg	178	179	168	169	169	168	119	133	41.0-170.0
HCO₃, mM/L	15	12	15	13	16	13	15	13	1.0-16.0
ESC, %	3	8	2	4	4	7	17	22	15.0-37.0
HSR, %	72	90	41	66	63	67	93	97	67.0-100.0
Morphology score	200	200	200	200	200	200	382	387	265.0-400.0
Glucose, mg/dL	381	504	390	405	388	540	375	393	344.0-466.0
P-selectin, % pos	2	4	17	13	3	3	16	9	NA
Annexin V, % pos	11.5	12.6	13.0	41.7	15.6	10.4	10.3	8.1	3.7-12.4

	UDP-galactose–treated, 4°C-stored*				Control 4°C-stored†		Control 22°-stored†		Normal range
	Vol 1	Vol 2	Vol 3	Vol 4	Vol 1	Vol 3	Vol 2	Vol 4	Normal range
Platelet count, × 10¹¹	1.75	1.97	1.69	1.88	1.74	1.81	2.19	1.89	—
pH	7.3	7.2	7.2	7.2	7.3	7.2	7.3	7.3	6.4-7.2
pCO₂, mmHg	29	29	36	26	31	28	23	15	9.0-47.0
pO₂, mmHg	178	179	168	169	169	168	119	133	41.0-170.0
HCO₃, mM/L	15	12	15	13	16	13	15	13	1.0-16.0
ESC, %	3	8	2	4	4	7	17	22	15.0-37.0
HSR, %	72	90	41	66	63	67	93	97	67.0-100.0
Morphology score	200	200	200	200	200	200	382	387	265.0-400.0
Glucose, mg/dL	381	504	390	405	388	540	375	393	344.0-466.0
P-selectin, % pos	2	4	17	13	3	3	16	9	NA
Annexin V, % pos	11.5	12.6	13.0	41.7	15.6	10.4	10.3	8.1	3.7-12.4

ESC indicates extent of shape change; HSR, hypotonic shock response; and —, not applicable.

A Units are UDP-galactosylated–treated, 4°C-stored platelets.

B Units are control platelets stored at 4°C or 22°C.