Table 1 Transplantation models... | American Society of Hematology

Table 1

Transplantation models

Experimental models	MHC haplotype		MHC disparity	Donor cells
	Recipient	Donor		TCD BM	T cells
	Recipient	Donor		Genotype	Subsets	Genotype
[B6→BDF₁] (BM/T)
WT/−	H-2^b/d	H-2^b	MHC I and II	WT	—	—
WT/WT	H-2^b/d	H-2^b	MHC I and II	WT	CD4/CD8	WT
lpr/−	H-2^b/d	H-2^b	MHC I and II	Fas^lpr/lpr	—	—
lpr/WT	H-2^b/d	H-2^b	MHC I and II	Fas^lpr/lpr	CD4/CD8	WT
WT/gld	H-2^b/d	H-2^b	MHC I and II	WT	CD4/CD8	FasL^{gld /gld}
[B6→bm₁]	H-2^bm1	H-2^b	MHC I	WT	CD8	WT
[B6→bm₁₂]	H-2^bm12	H-2^b	MHC II	WT	CD4	WT
[B6^{gld /gld} →bm₁₂]	H-2^bm12	H-2^b	MHC II	WT	CD4	FasL^{gld /gld}

Experimental models	MHC haplotype		MHC disparity	Donor cells
	Recipient	Donor		TCD BM	T cells
	Recipient	Donor		Genotype	Subsets	Genotype
[B6→BDF₁] (BM/T)
WT/−	H-2^b/d	H-2^b	MHC I and II	WT	—	—
WT/WT	H-2^b/d	H-2^b	MHC I and II	WT	CD4/CD8	WT
lpr/−	H-2^b/d	H-2^b	MHC I and II	Fas^lpr/lpr	—	—
lpr/WT	H-2^b/d	H-2^b	MHC I and II	Fas^lpr/lpr	CD4/CD8	WT
WT/gld	H-2^b/d	H-2^b	MHC I and II	WT	CD4/CD8	FasL^{gld /gld}
[B6→bm₁]	H-2^bm1	H-2^b	MHC I	WT	CD8	WT
[B6→bm₁₂]	H-2^bm12	H-2^b	MHC II	WT	CD4	WT
[B6^{gld /gld} →bm₁₂]	H-2^bm12	H-2^b	MHC II	WT	CD4	FasL^{gld /gld}

Congenic markers of each donor-recipient pair is otherwise indicated. lpr and gld are loss-of-function mutation of Fas and FasL, respectively. Groups are labeled as source of BM/source of splenic T cells (BM/T).