Proteins from KU812 total cell lysate purified on dasatinib-matrix
| Entrez name . | Description . | MW, kDa . | Protein score . | Unique peptides . | SC, % . |
|---|---|---|---|---|---|
| BTK | Bruton agammaglobulinemia tyrosine kinase | 76.2 | 1818 | 31 | 49.2 |
| LYN | Tyrosine-protein kinase LYN | 58.6 | 1432 | 18 | 36.9 |
| CSK | c-Src tyrosine kinase | 50.7 | 1113 | 17 | 42.4 |
| EPHB4 | EPH receptor B4 | 108.3 | 432 | 13 | 16.3 |
| MAPK14 | Mitogen-activated protein kinase 14 (p38α) | 41.3 | 275 | 12 | 33.1 |
| YES1 | Proto-oncogene tyrosine-protein kinase YES | 60.8 | 564 | 9 | 17.3 |
| TEC | TEC protein tyrosine kinase | 73.6 | 272 | 9 | 15.8 |
| ABL1 | Proto-oncogene tyrosine-protein kinase ABL1 | 122.9 | 636 | 9 | 11.7 |
| SRC | Tyrosine-protein kinase SRC-1 | 59.8 | 556 | 8 | 15.7 |
| KIT | v-KIT Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog | 109.9 | 184 | 6 | 5.6 |
| BCR | Breakpoint cluster region | 137.7 | 414 | 6 | 5.8 |
| FYN | Protein-tyrosine kinase FYN | 54.5 | 237 | 5 | 9.5 |
| EPHA5 | EPH receptor A5 | 114.8 | 105 | 5 | 5.5 |
| PRO3078 | — | 7.7 | 308 | 4 | 60.3 |
| ZAK | Sterile alpha motif and leucine zipper containing kinase AZK | 51.6 | 82 | 3 | 5.9 |
| HSPA8 | Heat shock 70kDa protein 8 | 70.9 | 88 | 3 | 5.7 |
| FRK | FYN-related kinase | 58.3 | 90 | 3 | 5.3 |
| ABL2 | v-ABL Abelson murine leukemia viral oncogene homolog 2 (Abelson-related gene) | 124.6 | 122 | 3 | 2.5 |
| PPAT | Phosphoribosyl pyrophosphate amidotransferase | 57.4 | 81 | 2 | 4.3 |
| FGR | Gardner-Rasheed feline sarcoma viral (v-FGR) oncogene homolog | 59.5 | 69 | 2 | 3.4 |
| Entrez name . | Description . | MW, kDa . | Protein score . | Unique peptides . | SC, % . |
|---|---|---|---|---|---|
| BTK | Bruton agammaglobulinemia tyrosine kinase | 76.2 | 1818 | 31 | 49.2 |
| LYN | Tyrosine-protein kinase LYN | 58.6 | 1432 | 18 | 36.9 |
| CSK | c-Src tyrosine kinase | 50.7 | 1113 | 17 | 42.4 |
| EPHB4 | EPH receptor B4 | 108.3 | 432 | 13 | 16.3 |
| MAPK14 | Mitogen-activated protein kinase 14 (p38α) | 41.3 | 275 | 12 | 33.1 |
| YES1 | Proto-oncogene tyrosine-protein kinase YES | 60.8 | 564 | 9 | 17.3 |
| TEC | TEC protein tyrosine kinase | 73.6 | 272 | 9 | 15.8 |
| ABL1 | Proto-oncogene tyrosine-protein kinase ABL1 | 122.9 | 636 | 9 | 11.7 |
| SRC | Tyrosine-protein kinase SRC-1 | 59.8 | 556 | 8 | 15.7 |
| KIT | v-KIT Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog | 109.9 | 184 | 6 | 5.6 |
| BCR | Breakpoint cluster region | 137.7 | 414 | 6 | 5.8 |
| FYN | Protein-tyrosine kinase FYN | 54.5 | 237 | 5 | 9.5 |
| EPHA5 | EPH receptor A5 | 114.8 | 105 | 5 | 5.5 |
| PRO3078 | — | 7.7 | 308 | 4 | 60.3 |
| ZAK | Sterile alpha motif and leucine zipper containing kinase AZK | 51.6 | 82 | 3 | 5.9 |
| HSPA8 | Heat shock 70kDa protein 8 | 70.9 | 88 | 3 | 5.7 |
| FRK | FYN-related kinase | 58.3 | 90 | 3 | 5.3 |
| ABL2 | v-ABL Abelson murine leukemia viral oncogene homolog 2 (Abelson-related gene) | 124.6 | 122 | 3 | 2.5 |
| PPAT | Phosphoribosyl pyrophosphate amidotransferase | 57.4 | 81 | 2 | 4.3 |
| FGR | Gardner-Rasheed feline sarcoma viral (v-FGR) oncogene homolog | 59.5 | 69 | 2 | 3.4 |
KU812 proteins were purified on dasatinib-matrix, cleaned up only for keratin. Proteins are sorted by the number of their unique peptides identified. The BCR-ABL fusion protein, which as a whole is not represented in the IPI database, is split into its 2 components, BCR and ABL1. Protein scores and sequence coverage (SC) are based on unique peptides. Protein scores are Mascot standard scores.
MW indicates molecular weight in kDa as defined by the particular IPI database entry; and —, no description available in IPI database.