Table 6 Allele frequencies in clinically... | American Society of Hematology

Table 6

Allele frequencies in clinically distinct subgroups of the CLL cohort

CLL subgroup	Allele frequency			P vs CLL	P vs counterpart
CLL subgroup	No.	C	G	P vs CLL	P vs counterpart
Sex
Female	105	0.82	0.18	.38	.12
Male	143	0.77	0.23	.56	.04
Binet stage
A+C	195	0.80	0.20	.43	.03
B	49	0.74	0.26	.40	.27
Affected LN areas
2 or less	188	0.81	0.19	.50	<.001
More than 2	50	0.66	0.34	.14	.051
Spleen size
Normal	191	0.81	0.19	.29	<.001
Enlarged	51	0.72	0.28	.11	.027
LDH
450 IU/L or less	192	0.81	0.19	.01	.003
More than 450 IU/L	34	0.65	0.35	.64	<.001
Lines of therapy
Less than 2	170	0.81	0.19	.41	<.001
2 or more	67	0.72	0.28	.11	.018

CLL subgroup	Allele frequency			P vs CLL	P vs counterpart
CLL subgroup	No.	C	G	P vs CLL	P vs counterpart
Sex
Female	105	0.82	0.18	.38	.12
Male	143	0.77	0.23	.56	.04
Binet stage
A+C	195	0.80	0.20	.43	.03
B	49	0.74	0.26	.40	.27
Affected LN areas
2 or less	188	0.81	0.19	.50	<.001
More than 2	50	0.66	0.34	.14	.051
Spleen size
Normal	191	0.81	0.19	.29	<.001
Enlarged	51	0.72	0.28	.11	.027
LDH
450 IU/L or less	192	0.81	0.19	.01	.003
More than 450 IU/L	34	0.65	0.35	.64	<.001
Lines of therapy
Less than 2	170	0.81	0.19	.41	<.001
2 or more	67	0.72	0.28	.11	.018