Immunophenotype and classification of histiocytic or dendritic cell tumors
| Case . | CD68 . | CD163 . | Lysozyme . | S100 . | CD1a . | CD20 . | PAX5 . | PU.1 . | CEBPβ . | Classification . |
|---|---|---|---|---|---|---|---|---|---|---|
| 1 | + | + | + | + | − | − | − | + | + | Histiocytic sarcoma with DC differentiation |
| 2 | + | − | − | + | − | − | − | + | + | Histiocytic sarcoma with DC differentiation |
| 3 | + | + | + | + | nd | − | nd | nd | nd | Histiocytic sarcoma with DC differentiation |
| 4 | F | + | − | + | F | − | − | + | + | Interdigitating DC sarcoma |
| 5 | + | + | + | − | − | − | − | + | + | Histiocytic sarcoma |
| 6 | + | nd | + | + | nd | − | − | + | + | Histiocytic sarcoma with DC differentiation |
| 7 | + | + | F | + | + | − | − | nd | nd | Histiocytic sarcoma with DC differentiation |
| 8 | + | + | + | − | − | − | − | + | + | Histiocytic sarcoma |
| Case . | CD68 . | CD163 . | Lysozyme . | S100 . | CD1a . | CD20 . | PAX5 . | PU.1 . | CEBPβ . | Classification . |
|---|---|---|---|---|---|---|---|---|---|---|
| 1 | + | + | + | + | − | − | − | + | + | Histiocytic sarcoma with DC differentiation |
| 2 | + | − | − | + | − | − | − | + | + | Histiocytic sarcoma with DC differentiation |
| 3 | + | + | + | + | nd | − | nd | nd | nd | Histiocytic sarcoma with DC differentiation |
| 4 | F | + | − | + | F | − | − | + | + | Interdigitating DC sarcoma |
| 5 | + | + | + | − | − | − | − | + | + | Histiocytic sarcoma |
| 6 | + | nd | + | + | nd | − | − | + | + | Histiocytic sarcoma with DC differentiation |
| 7 | + | + | F | + | + | − | − | nd | nd | Histiocytic sarcoma with DC differentiation |
| 8 | + | + | + | − | − | − | − | + | + | Histiocytic sarcoma |
DC indicates dendritic cell; F, focal; and nd, not done.