Table 3 Genetic findings in follicular... | American Society of Hematology

Table 3

Genetic findings in follicular lymphoma and histiocytic or dendritic cell tumors

Case	t(14;18) by FISH	BCL2/JH MBR rearrangement by PCR	Clonal IGH rearrangement by PCR	Sequence similarity between FL and H/DC tumor
1-FL	+	+	+	+
1-HD/C	+	+	+	+
2-FL	+	+	+	+
2-HD/C	+	+	+	+
3-FL	+	+	+	unsat
3-HD/C	+	+	+	unsat
4-FL	+	−	+	+
4-HD/C	+	−	+	+
5-FL	+	+	+	+
5-HD/C	+	+	+	+
6-FL	unsat	+	+	unsat
6-HD/C	unsat	+	+	unsat
7-FL	unsat*	nd	+	nd
7-HD/C	+	nd	Not evaluable	nd
8-FL	unsat	+	−	+†
8-HD/C	unsat	+	−	+†

Case	t(14;18) by FISH	BCL2/JH MBR rearrangement by PCR	Clonal IGH rearrangement by PCR	Sequence similarity between FL and H/DC tumor
1-FL	+	+	+	+
1-HD/C	+	+	+	+
2-FL	+	+	+	+
2-HD/C	+	+	+	+
3-FL	+	+	+	unsat
3-HD/C	+	+	+	unsat
4-FL	+	−	+	+
4-HD/C	+	−	+	+
5-FL	+	+	+	+
5-HD/C	+	+	+	+
6-FL	unsat	+	+	unsat
6-HD/C	unsat	+	+	unsat
7-FL	unsat*	nd	+	nd
7-HD/C	+	nd	Not evaluable	nd
8-FL	unsat	+	−	+†
8-HD/C	unsat	+	−	+†

FL indicates follicular lymphoma; H/DC, histiocytic or dendritic cell; nd, not done; and unsat, unsatisfactory.

Poor signal in the FL component of the specimen precluded interpretation.

Clonal rearrangement not identified with Fr 2 or Fr3 primer sets. Sequencing performed on BCL2/JH product.