Table 3 SigPathway results: PCNSL versus... | American Society of Hematology

Table 3

SigPathway results: PCNSL versus nodal DLBCL

	Gene set category	Pathway	Set size	% up	NTk rank	NEk rank
1	KEGG:00330	Arginine and proline metabolism	38	68	11	2
2	GO:0016066	Cellular defense response (sensu Vertebrata)	12	75	10	6
3	KEGG:04512	ECM-receptor interaction	47	19	3	16
4	GO:0042087	Cell-mediated immune response	11	73	16	3
5	GO:0042088	T-helper 1 type immune response	11	73	16	3
6	BioCyc	Fatty acid oxidation pathway	14	71	17	10
7	GO:0005604	Basement membrane	23	4	2	28
8	KEGG:04510	Focal adhesion	135	38	7	25
9	GO:0016126	Sterol biosynthesis	22	23	30	8
10	GO:0001817	Regulation of cytokine production	16	75	20	26
11	GO:0019888	Protein phosphatase regulator activity	32	22	36	12
12	GO:0050954	Sensory perception of mechanical stimulus	39	38	48	4
13	GO:0007605	Sensory perception of sound	39	38	48	4
14	GO:0019208	Phosphatase regulator activity	33	24	54	9
15	GO:0001816	Cytokine production	17	76	18	48
16	GO:0042089	Cytokine biosynthesis	17	76	18	48
17	GO:0042995	Cell projection	36	19	47	19
18	GO:0042157	Lipoprotein metabolism	25	68	68	5
19	GO:0016836	Hydrolyase activity	29	76	6	77
20	KEGG:04662	B-cell receptor signaling pathway	45	73	9	80
21	GO:0005201	Extracellular matrix structural constituent	40	23	4	93
22	GO:0007588	Excretion	16	69	96	7
23	GO:0042158	Lipoprotein biosynthesis	16	75	96	14
24	GO:0006497	Protein amino acid lipidation	16	75	96	14
25	GO:0007409	Axonogenesis	18	61	96	15
26	GO:0050900	Immune cell migration	10	60	96	17
27	GO:0030595	Immune cell chemotaxis	10	60	96	17
28	GO:0048468	Cell development	34	59	96	18
29	GO:0006631	Fatty acid metabolism	80	60	5	124
30	GO:0005605	Basal lamina	14	0	12	124

	Gene set category	Pathway	Set size	% up	NTk rank	NEk rank
1	KEGG:00330	Arginine and proline metabolism	38	68	11	2
2	GO:0016066	Cellular defense response (sensu Vertebrata)	12	75	10	6
3	KEGG:04512	ECM-receptor interaction	47	19	3	16
4	GO:0042087	Cell-mediated immune response	11	73	16	3
5	GO:0042088	T-helper 1 type immune response	11	73	16	3
6	BioCyc	Fatty acid oxidation pathway	14	71	17	10
7	GO:0005604	Basement membrane	23	4	2	28
8	KEGG:04510	Focal adhesion	135	38	7	25
9	GO:0016126	Sterol biosynthesis	22	23	30	8
10	GO:0001817	Regulation of cytokine production	16	75	20	26
11	GO:0019888	Protein phosphatase regulator activity	32	22	36	12
12	GO:0050954	Sensory perception of mechanical stimulus	39	38	48	4
13	GO:0007605	Sensory perception of sound	39	38	48	4
14	GO:0019208	Phosphatase regulator activity	33	24	54	9
15	GO:0001816	Cytokine production	17	76	18	48
16	GO:0042089	Cytokine biosynthesis	17	76	18	48
17	GO:0042995	Cell projection	36	19	47	19
18	GO:0042157	Lipoprotein metabolism	25	68	68	5
19	GO:0016836	Hydrolyase activity	29	76	6	77
20	KEGG:04662	B-cell receptor signaling pathway	45	73	9	80
21	GO:0005201	Extracellular matrix structural constituent	40	23	4	93
22	GO:0007588	Excretion	16	69	96	7
23	GO:0042158	Lipoprotein biosynthesis	16	75	96	14
24	GO:0006497	Protein amino acid lipidation	16	75	96	14
25	GO:0007409	Axonogenesis	18	61	96	15
26	GO:0050900	Immune cell migration	10	60	96	17
27	GO:0030595	Immune cell chemotaxis	10	60	96	17
28	GO:0048468	Cell development	34	59	96	18
29	GO:0006631	Fatty acid metabolism	80	60	5	124
30	GO:0005605	Basal lamina	14	0	12	124