Table 4 SigPathway results: PCNSL versus... | American Society of Hematology

Table 4

SigPathway results: PCNSL versus extranodal DLBCL

	Gene set category	Pathway	Set size	% up	NTk rank	NEk rank
1	GO:0004857	Enzyme inhibitor activity	128	30	14	2
2	KEGG:01430	Cell communication	53	28	5	15
3	KEGG:04510	Focal adhesion	135	33	7	19
4	KEGG:04512	ECM-receptor interaction	47	21	3	27
5	GO:0031497	Chromatin assembly	54	20	13	18
6	KEGG:04210	Apoptosis	51	29	15	16
7	GO:0000785	Chromatin	94	32	12	21
8	GO:0005604	Basement membrane	23	17	8	26
9	GO:0006695	Cholesterol biosynthesis	15	27	32	8
10	GO:0007059	Chromosome segregation	25	12	6	38
11	GO:0043161	Proteasomal ubiquitin-dependent protein catabolism	11	9	38	9
12	GO:0001501	Skeletal development	47	23	16	32
13	GO:0006334	Nucleosome assembly	52	19	17	40
14	BioCarta	Ceramide signaling pathway	14	21	49	13
15	GO:0043062	Extracellular structure organization and biogenesis	11	9	9	56
16	GO:0030198	Extracellular matrix organization and biogenesis	11	9	9	56
17	BioCarta	Caspase cascade in apoptosis	17	29	63	11
18	GO:0016126	Sterol biosynthesis	22	32	73	10
19	KEGG:00220	Urea cycle and metabolism of amino groups	18	56	72	20
20	GO:0005201	Extracellular matrix structural constituent	40	23	1	116
21	GO:0005694	Chromosome	190	35	10	110
22	GO:0005581	Collagen	15	13	4	137
23	GO:0016810	Hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds	38	61	138.5	5
24	GO:0000786	Nucleosome	39	18	21	137
25	GO:0009064	Glutamine family amino acid metabolism	23	65	138.5	22
26	GO:0005605	Basal lamina	14	14	19	166
27	GO:0006928	Cell motility	130	38	18	176
28	GO:0040011	Locomotion	130	38	18	176
29	GO:0051674	Localization of cell	130	38	18	176
30	GO:0005578	Extracellular matrix (sensu Metazoa)	102	24	2	212.5

	Gene set category	Pathway	Set size	% up	NTk rank	NEk rank
1	GO:0004857	Enzyme inhibitor activity	128	30	14	2
2	KEGG:01430	Cell communication	53	28	5	15
3	KEGG:04510	Focal adhesion	135	33	7	19
4	KEGG:04512	ECM-receptor interaction	47	21	3	27
5	GO:0031497	Chromatin assembly	54	20	13	18
6	KEGG:04210	Apoptosis	51	29	15	16
7	GO:0000785	Chromatin	94	32	12	21
8	GO:0005604	Basement membrane	23	17	8	26
9	GO:0006695	Cholesterol biosynthesis	15	27	32	8
10	GO:0007059	Chromosome segregation	25	12	6	38
11	GO:0043161	Proteasomal ubiquitin-dependent protein catabolism	11	9	38	9
12	GO:0001501	Skeletal development	47	23	16	32
13	GO:0006334	Nucleosome assembly	52	19	17	40
14	BioCarta	Ceramide signaling pathway	14	21	49	13
15	GO:0043062	Extracellular structure organization and biogenesis	11	9	9	56
16	GO:0030198	Extracellular matrix organization and biogenesis	11	9	9	56
17	BioCarta	Caspase cascade in apoptosis	17	29	63	11
18	GO:0016126	Sterol biosynthesis	22	32	73	10
19	KEGG:00220	Urea cycle and metabolism of amino groups	18	56	72	20
20	GO:0005201	Extracellular matrix structural constituent	40	23	1	116
21	GO:0005694	Chromosome	190	35	10	110
22	GO:0005581	Collagen	15	13	4	137
23	GO:0016810	Hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds	38	61	138.5	5
24	GO:0000786	Nucleosome	39	18	21	137
25	GO:0009064	Glutamine family amino acid metabolism	23	65	138.5	22
26	GO:0005605	Basal lamina	14	14	19	166
27	GO:0006928	Cell motility	130	38	18	176
28	GO:0040011	Locomotion	130	38	18	176
29	GO:0051674	Localization of cell	130	38	18	176
30	GO:0005578	Extracellular matrix (sensu Metazoa)	102	24	2	212.5