Up- or down-regulated genes by both the NUP98/HHEX and the NUP98/HOXA9 fusions in primary murine bone marrow cells
| Gene name . | Fold change* . | |
|---|---|---|
| NUP98/HOXA9 . | NUP98/HHEX . | |
| Prion protein (Prnp) | 2.3 | 2.3 |
| Carbonic anhydrase 1(Car1) | 4.7 | 1.5 |
| Hemoglobin, beta adult minor chain (Hbb-b2) | 3.1 | 3.4 |
| CD28 antigen | 4.2 | 1.8 |
| Rab38, member of RAS oncogene family (Rab38) | 2.4 | 1.6 |
| Hemoglobin alpha, adult chain 1 (Hba-a1) | 1.7 | 1.9 |
| Myosin light chain 2, precursor lymphocyte-specific (Mylc2pl) | 4.7 | 1.9 |
| Pre B-cell leukemia transcription factor 3 (Pbx3) | 5.4 | 1.9 |
| Myocyte enhancer factor 2C (Mef2c) | 2.0 | 1.6 |
| Calcitonin receptor-like (Calcrl) | 5.6 | 1.7 |
| Transcription factor 12 (Tcf12) | 1.8 | 2.1 |
| Hemoglobin alpha, adult chain 1 (Hba-a1) | 1.7 | 2.0 |
| Prion protein (Prnp) | 3.2 | 3.1 |
| Homeo box A5 (Hoxa5) | 12.1 | 1.7 |
| RIKEN cDNA 4732435N03 gene | 2.3 | 1.5 |
| Hemoglobin alpha, adult chain 1 (Hba-a1) | 2.4 | 2.9 |
| Homeo box A9 (Hoxa9) | 11.3 | 2.4 |
| Cysteine-rich secretory protein 1 (Crisp1) | 126.5 | −1.6 |
| Kit oncogene (Kit) | −2.8 | −1.9 |
| Small muscle protein, X-linked (Smpx) | −2.4 | −2.2 |
| Aldo-keto reductase family 1, member C18 (Akr1c18) | −2.8 | 2.6 |
| Complement component 3a receptor 1 (C3ar1) | −1.9 | −2.2 |
| Cytokine-dependent hematopoietic cell linker (Clnk) | −2.5 | −1.7 |
| Heparan sulfate 6-O-sulfotransferase 2 (Hs6st2) | −2.3 | −1.9 |
| 3'-phosphoadenosine 5'-phosphosulfate synthase 2 (Papss2) | −2.5 | −1.6 |
| Mast cell protease 1 (Mcpt1) | −10.4 | −4.2 |
| Reprimo, TP53 dependent G2 arrest mediator candidate (Rprm) | −1.9 | −1.8 |
| Elastase 2, neutrophil (Ela2) | −2.4 | −1.6 |
| Mast cell protease 4 (Mcpt4) | −10.0 | −3.1 |
| Tryptase alpha/beta 1 (Tpsab1) | −15.4 | −2.2 |
| Heparan sulfate 6-O-sulfotransferase 2 (Hs6st2) | −4.8 | −3.0 |
| Kit oncogene (Kit) | −2.5 | −1.9 |
| Gene name . | Fold change* . | |
|---|---|---|
| NUP98/HOXA9 . | NUP98/HHEX . | |
| Prion protein (Prnp) | 2.3 | 2.3 |
| Carbonic anhydrase 1(Car1) | 4.7 | 1.5 |
| Hemoglobin, beta adult minor chain (Hbb-b2) | 3.1 | 3.4 |
| CD28 antigen | 4.2 | 1.8 |
| Rab38, member of RAS oncogene family (Rab38) | 2.4 | 1.6 |
| Hemoglobin alpha, adult chain 1 (Hba-a1) | 1.7 | 1.9 |
| Myosin light chain 2, precursor lymphocyte-specific (Mylc2pl) | 4.7 | 1.9 |
| Pre B-cell leukemia transcription factor 3 (Pbx3) | 5.4 | 1.9 |
| Myocyte enhancer factor 2C (Mef2c) | 2.0 | 1.6 |
| Calcitonin receptor-like (Calcrl) | 5.6 | 1.7 |
| Transcription factor 12 (Tcf12) | 1.8 | 2.1 |
| Hemoglobin alpha, adult chain 1 (Hba-a1) | 1.7 | 2.0 |
| Prion protein (Prnp) | 3.2 | 3.1 |
| Homeo box A5 (Hoxa5) | 12.1 | 1.7 |
| RIKEN cDNA 4732435N03 gene | 2.3 | 1.5 |
| Hemoglobin alpha, adult chain 1 (Hba-a1) | 2.4 | 2.9 |
| Homeo box A9 (Hoxa9) | 11.3 | 2.4 |
| Cysteine-rich secretory protein 1 (Crisp1) | 126.5 | −1.6 |
| Kit oncogene (Kit) | −2.8 | −1.9 |
| Small muscle protein, X-linked (Smpx) | −2.4 | −2.2 |
| Aldo-keto reductase family 1, member C18 (Akr1c18) | −2.8 | 2.6 |
| Complement component 3a receptor 1 (C3ar1) | −1.9 | −2.2 |
| Cytokine-dependent hematopoietic cell linker (Clnk) | −2.5 | −1.7 |
| Heparan sulfate 6-O-sulfotransferase 2 (Hs6st2) | −2.3 | −1.9 |
| 3'-phosphoadenosine 5'-phosphosulfate synthase 2 (Papss2) | −2.5 | −1.6 |
| Mast cell protease 1 (Mcpt1) | −10.4 | −4.2 |
| Reprimo, TP53 dependent G2 arrest mediator candidate (Rprm) | −1.9 | −1.8 |
| Elastase 2, neutrophil (Ela2) | −2.4 | −1.6 |
| Mast cell protease 4 (Mcpt4) | −10.0 | −3.1 |
| Tryptase alpha/beta 1 (Tpsab1) | −15.4 | −2.2 |
| Heparan sulfate 6-O-sulfotransferase 2 (Hs6st2) | −4.8 | −3.0 |
| Kit oncogene (Kit) | −2.5 | −1.9 |
The cutoff level is 1.5-fold when compared with pMSCV-EGFP–mock infected cells. The full list of genes is provided in Tables S2,S3.
P < .05