Table 4

Role of splenomegaly

With splenomegaly, no. patientsNo splenomegaly, no. patientsP for positive association with splenomegaly
Cytopenias alone 21 12 < .001 
Hepatomegaly 22 < .001 
Granuloma 17 11 < .001 
Enteropathy 14 15 .03 
Bronchiectasis 33 51 .04 
Cytopenias + solid organ autoimmunity .2 
Solid organ–specific autoimmunity alone 28 65 1.0 
Total 100 234  
With splenomegaly, no. patientsNo splenomegaly, no. patientsP for positive association with splenomegaly
Cytopenias alone 21 12 < .001 
Hepatomegaly 22 < .001 
Granuloma 17 11 < .001 
Enteropathy 14 15 .03 
Bronchiectasis 33 51 .04 
Cytopenias + solid organ autoimmunity .2 
Solid organ–specific autoimmunity alone 28 65 1.0 
Total 100 234  

Numbers and types of complications in patients with and without splenomegaly and the level of significance for each.

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