Table 2

Combination Index values for the effects of PHA-739358 and imatinib

PHA-738359 plus IMED50ED75ED90
K562 0.25 0.44 0.79 
BV173 0.37 0.51 0.70 
BaF3-p210 0.40 0.54 0.73 
BaF3-M351T 0.56 0.59 0.63 
BaF3-E255K 0.89 0.86 0.83 
BaF3-T315I 0.90 1.16 1.51 
PHA-738359 plus IMED50ED75ED90
K562 0.25 0.44 0.79 
BV173 0.37 0.51 0.70 
BaF3-p210 0.40 0.54 0.73 
BaF3-M351T 0.56 0.59 0.63 
BaF3-E255K 0.89 0.86 0.83 
BaF3-T315I 0.90 1.16 1.51 
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