Gene elements up-regulated and down-regulated by ceramide
| . | GenBank42 accession no. . | Function/category . | Ratio of mean . |
|---|---|---|---|
| Up-regulated genes | |||
| Thioredoxin interacting protein (Txnip) | BG086605 | Energy/metabolism | 5.307 |
| Pend-immediate early response (Lerepo1) | BG080722 | — | 3.360 |
| CDC-like kinase (Clk) | BG065099 | Signal transduction | 2.883 |
| Interleukin-16 (IL16) | BG080207 | Signal transduction | 2.658 |
| Aplysia ras-related homolog B (Arhb) | BG076893 | — | 2.555 |
| 5′-TG-3′-interacting factor (Tgif) | BG088209 | Transcription/chromatin | 2.547 |
| Down-regulated genes | |||
| Inhibitor of DNA binding 2 (Idb) | BG073126 | Transcription/chromatin | 0.223 |
| Solute carrier family 2 (Slc2a1) | BG064126 | Matrix/structural proteins | 0.472 |
| Heme oxygenase decycling 1 (Hmox) | BG077732 | Matrix/structural proteins | 0.493 |
| . | GenBank42 accession no. . | Function/category . | Ratio of mean . |
|---|---|---|---|
| Up-regulated genes | |||
| Thioredoxin interacting protein (Txnip) | BG086605 | Energy/metabolism | 5.307 |
| Pend-immediate early response (Lerepo1) | BG080722 | — | 3.360 |
| CDC-like kinase (Clk) | BG065099 | Signal transduction | 2.883 |
| Interleukin-16 (IL16) | BG080207 | Signal transduction | 2.658 |
| Aplysia ras-related homolog B (Arhb) | BG076893 | — | 2.555 |
| 5′-TG-3′-interacting factor (Tgif) | BG088209 | Transcription/chromatin | 2.547 |
| Down-regulated genes | |||
| Inhibitor of DNA binding 2 (Idb) | BG073126 | Transcription/chromatin | 0.223 |
| Solute carrier family 2 (Slc2a1) | BG064126 | Matrix/structural proteins | 0.472 |
| Heme oxygenase decycling 1 (Hmox) | BG077732 | Matrix/structural proteins | 0.493 |
10I cells were treated with or without 40 μM C2-ceramide for 2 hours. Cells were collected, and total RNA was purified followed by cDNA synthesis. Using microarray analysis, the up-regulated genes and down-regulated genes are shown.
— indicates no data.