Non-fVIII genes associated with inhibitor formation
| Gene . | Reference . | Severe hemophilia A OR (95% CI) . | All hemophilia A OR (95% CI) . |
|---|---|---|---|
| DQA0102 | 20 | 2.7 (1.2-5.9) | |
| IL10 allele 134 | 22 | 5.4 (2.1-9.5) | 4.4 (2.1-13.7) |
| TNF-a −308 A/A genotype | 21 | 19.2 (2.4-156.5) | 4.0 (2.1-13.7) |
| CTLA4 −318 T allele | 23 | 0.3 (0.1-0.8) |
| Gene . | Reference . | Severe hemophilia A OR (95% CI) . | All hemophilia A OR (95% CI) . |
|---|---|---|---|
| DQA0102 | 20 | 2.7 (1.2-5.9) | |
| IL10 allele 134 | 22 | 5.4 (2.1-9.5) | 4.4 (2.1-13.7) |
| TNF-a −308 A/A genotype | 21 | 19.2 (2.4-156.5) | 4.0 (2.1-13.7) |
| CTLA4 −318 T allele | 23 | 0.3 (0.1-0.8) |