Complete response and overall survival models: multivariate analyses
| Factor . | Response (logistic model) . | Survival (log-logistic model) . | ||
|---|---|---|---|---|
| Parametera . | P . | Parametera . | P . | |
| Age < 60 | ||||
| Ageb | −0.867 ± 0.224 | < .001 | −0.829 ± 0.174 | < .001 |
| Etiologyc | −0.784 ± 0.206 | < .001 | −0.483 ± 0.161 | .003 |
| Diagnosis to treatment intervald | −0.030 ± 0.009 | < .001 | −0.024 ± 0.007 | .001 |
| Etiology and WBCe | −0.576 ± 0.286 | .007 | ||
| Centerf | −0.576 ± 0.286 | .04 | −0.107 ± 0.222 | .63 |
| Intercept | 2.520 ± 0.335 | 5.401 ± 0.245 | ||
| Scale | 1.062 ± 0.045 | |||
| . | If treatment delay is included, then P value for delay = .63: . | . | If treatment delay is included, then P value for delay = .30: . | . |
| Age ≥ 60 | ||||
| Age | −0.032 ± 0.013d | .02d | −0.382 ± 0.132g | .004g |
| Etiology and WBCh | −0.902 ± 0.194 | < .001 | ||
| WBCi | −0.350 ± 0.132 | .008 | ||
| Centerf | −0.325 ± 0.228 | .15 | −0.014 ± 0.180 | .94 |
| Intercept | 2.841 ± 0.944 | 3.741 ± 0.187 | ||
| Scale | 0.964 ± 0.034 | |||
| Factor . | Response (logistic model) . | Survival (log-logistic model) . | ||
|---|---|---|---|---|
| Parametera . | P . | Parametera . | P . | |
| Age < 60 | ||||
| Ageb | −0.867 ± 0.224 | < .001 | −0.829 ± 0.174 | < .001 |
| Etiologyc | −0.784 ± 0.206 | < .001 | −0.483 ± 0.161 | .003 |
| Diagnosis to treatment intervald | −0.030 ± 0.009 | < .001 | −0.024 ± 0.007 | .001 |
| Etiology and WBCe | −0.576 ± 0.286 | .007 | ||
| Centerf | −0.576 ± 0.286 | .04 | −0.107 ± 0.222 | .63 |
| Intercept | 2.520 ± 0.335 | 5.401 ± 0.245 | ||
| Scale | 1.062 ± 0.045 | |||
| . | If treatment delay is included, then P value for delay = .63: . | . | If treatment delay is included, then P value for delay = .30: . | . |
| Age ≥ 60 | ||||
| Age | −0.032 ± 0.013d | .02d | −0.382 ± 0.132g | .004g |
| Etiology and WBCh | −0.902 ± 0.194 | < .001 | ||
| WBCi | −0.350 ± 0.132 | .008 | ||
| Centerf | −0.325 ± 0.228 | .15 | −0.014 ± 0.180 | .94 |
| Intercept | 2.841 ± 0.944 | 3.741 ± 0.187 | ||
| Scale | 0.964 ± 0.034 | |||
Positive (negative) values indicate benefit (harm) with increasing values of the factor.
Coded age: 0 indicates ≤ 40; and 1, > 40.
0 indicates de novo; and 1, sAML.
Original, untransformed scale.
0 indicates de novo or sAML with WBC ≤ 8.5/mm3; and 1, sAML and WBC > 8.5/mm3.
0 indicates CCF; and 1, MDA.
Coded age: 0 indicates < 70; and 1, ≥70.
0 indicates de novo or sAML with WBC ≤ 5.0/mm3; and 1, sAML and WBC > 5.0/mm3.
Coded WBC, 0 indicates ≤ 5.0/mm3; and 1, > 5.0/mm3