Table 5 Complete response and overall... | American Society of Hematology

Table 5

Complete response and overall survival models: multivariate analyses including PS and cytogenetics

Factor	Response (logistic model)		Survival (log-logistic model)
Factor	Parameter^a	P	Parameter^a	P
Age < 60
Age^b	−0.761 ± 0.250	.002	−0.601 ± 0.177	< .001
Etiology^c	−0.578 ± 0.229	.01	−0.170 ± 0.161	.29
Diagnosis to treatment interval^d	−0.028 ± 0.009	.003	−0.018 ± 0.007	.009
Etiology and WBC^e	−0.873 ± 0.332	.009
Cytogenetics^f	−1.098 ± 0.192	< .001	−1.115 ± 0.141	< .001
PS^g	−0.209 ± 0.147	.155	−0.577 ± 0.115	< .001
Intercept	3.281 ± 0.355		6.819 ± 0.237
Scale			0.962 ± 0.043
	If treatment delay is included, then P value for delay = .49:		If treatment delay is included, then P value for delay = .94:
Age ≥ 60
Age	−0.029 ± 0.015^d	.05^d	−0.267 ± 0.132^h	.04^h
Etiology and WBCⁱ	−1.015 ± 0.216	< .001
WBC^j			−0.410 ± 0.134	.002
Cytogenetics^f	−0.998 ± 0.190	< .001	−0.917 ± 0.096	< .001
PS^g	−0.418 ± 0.128	.001	−0.749 ± 0.130	< .001
Intercept	2.841 ± 0.944		5.764 ± 0.218
Scale			0.882 ± 0.034

Factor	Response (logistic model)		Survival (log-logistic model)
Factor	Parameter^a	P	Parameter^a	P
Age < 60
Age^b	−0.761 ± 0.250	.002	−0.601 ± 0.177	< .001
Etiology^c	−0.578 ± 0.229	.01	−0.170 ± 0.161	.29
Diagnosis to treatment interval^d	−0.028 ± 0.009	.003	−0.018 ± 0.007	.009
Etiology and WBC^e	−0.873 ± 0.332	.009
Cytogenetics^f	−1.098 ± 0.192	< .001	−1.115 ± 0.141	< .001
PS^g	−0.209 ± 0.147	.155	−0.577 ± 0.115	< .001
Intercept	3.281 ± 0.355		6.819 ± 0.237
Scale			0.962 ± 0.043
	If treatment delay is included, then P value for delay = .49:		If treatment delay is included, then P value for delay = .94:
Age ≥ 60
Age	−0.029 ± 0.015^d	.05^d	−0.267 ± 0.132^h	.04^h
Etiology and WBCⁱ	−1.015 ± 0.216	< .001
WBC^j			−0.410 ± 0.134	.002
Cytogenetics^f	−0.998 ± 0.190	< .001	−0.917 ± 0.096	< .001
PS^g	−0.418 ± 0.128	.001	−0.749 ± 0.130	< .001
Intercept	2.841 ± 0.944		5.764 ± 0.218
Scale			0.882 ± 0.034

Positive (negative) values indicate benefit (harm) with increasing values of the factor.

Coded age: 0 indicates ≤ 40; and 1, > 40.

0 indicates de novo; and 1, sAML.

Original, untransformed scale.

0 indicates de novo or sAML with WBC ≤ 8.5/mm³; and 1, sAML and WBC > 8.5/mm³.

0 indicates favorable; 1, intermediate; and 2, unfavorable.

PS 0 versus 1 versus 2 versus 3-4.

Coded age: 0 indicates < 70; and 1, ≥ 70.

0 indicates de novo or sAML with WBC ≤ 5.0/mm³; and 1, sAML and WBC > 5.0/mm³.

Coded WBC: 0 indicates ≤ 5.0/mm³; and 1, > 5.0/mm³.