Clinicopathologic features of patients and their tumor response to H pylori eradication
| Characteristic . | H pylori–dependent, no. (%) . | H pylori–independent, no. (%) . | P . |
|---|---|---|---|
| No. (%) of patients | 16 (61.6) | 10 (38.4) | NS |
| Median age, y (range) | 60.5 (35-84) | 56 (21-83) | NS |
| Sex | |||
| Male | 3 (18.8) | 4 (40) | NS |
| Female | 13 (81.3) | 6 (60) | |
| Depth of tumor invasion* | |||
| Mucosa/submucosa | 9 (81.8) | 6 (60) | NS |
| Muscularis propria/serosa | 2 (18.2) | 4 (40) | |
| BAFF expression | |||
| Positive | 3 (18.7) | 7 (70) | .015 |
| Negative | 13 (82.3) | 3 (30) | |
| pAKT expression | |||
| Positive | 4 (25.0) | 7 (70) | .043 |
| Negative | 12 (75.0) | 3 (30) | |
| BCL3 expression | |||
| Nuclear/cytoplasmic | 4 (25.0) | 8 (80) | .014 |
| Cytoplasmic | 12 (75.0) | 2 (20) | |
| BCL10 expression | |||
| Nuclear/cytoplasmic | 1 (6.3) | 9 (90) | <.001 |
| Cytoplasmic | 15 (93.7) | 1 (10) | |
| NF-κB expression | |||
| Nuclear/cytoplasmic | 3 (18.8) | 9 (90) | .001 |
| Cytoplasmic | 13 (81.2) | 1 (10) | |
| Characteristic . | H pylori–dependent, no. (%) . | H pylori–independent, no. (%) . | P . |
|---|---|---|---|
| No. (%) of patients | 16 (61.6) | 10 (38.4) | NS |
| Median age, y (range) | 60.5 (35-84) | 56 (21-83) | NS |
| Sex | |||
| Male | 3 (18.8) | 4 (40) | NS |
| Female | 13 (81.3) | 6 (60) | |
| Depth of tumor invasion* | |||
| Mucosa/submucosa | 9 (81.8) | 6 (60) | NS |
| Muscularis propria/serosa | 2 (18.2) | 4 (40) | |
| BAFF expression | |||
| Positive | 3 (18.7) | 7 (70) | .015 |
| Negative | 13 (82.3) | 3 (30) | |
| pAKT expression | |||
| Positive | 4 (25.0) | 7 (70) | .043 |
| Negative | 12 (75.0) | 3 (30) | |
| BCL3 expression | |||
| Nuclear/cytoplasmic | 4 (25.0) | 8 (80) | .014 |
| Cytoplasmic | 12 (75.0) | 2 (20) | |
| BCL10 expression | |||
| Nuclear/cytoplasmic | 1 (6.3) | 9 (90) | <.001 |
| Cytoplasmic | 15 (93.7) | 1 (10) | |
| NF-κB expression | |||
| Nuclear/cytoplasmic | 3 (18.8) | 9 (90) | .001 |
| Cytoplasmic | 13 (81.2) | 1 (10) | |
NS indicates not significant; and EUS, endoscopic ultrasonography.
Evaluated by EUS (20 patients) and histologic examination of surgical specimens (1 patient).