Histologic characteristics of age-related EBV-positive B-cell LPDs and EBV-positive cHL
| . | Age-related EBV+ LPDs polymorphous type, n = 34 . | EBV+ cHL age 50 y older, n = 108 . | P . |
|---|---|---|---|
| Necrosis (%) | 12/22 (55) | 6/80 (8) | < .001 |
| Increasing of cytotoxic T cells (%) | 11/17 (65) | 19/73 (26) | < .001 |
| Immunophenotype (%) | |||
| CD20 | 32/32 (100) | 19/99 (19) | < .001 |
| CD15 | 0/27 (0) | 64/106 (60) | < .001 |
| CD30 | 19/27 (70) | 99/107 (93) | .002 |
| CD45RO | 4/12 (33) | 1/77 (1) | .001 |
| CD56 | 0/13 (0) | 0/21 (0) | > .99 |
| EBER | 34/34 (100) | 108/108 (100) | > .99 |
| LMP1 | 29/29 (100) | 45/52 (87) | .039 |
| EBNA2 | 7/28 (25) | 0/24 (0) | .008 |
| . | Age-related EBV+ LPDs polymorphous type, n = 34 . | EBV+ cHL age 50 y older, n = 108 . | P . |
|---|---|---|---|
| Necrosis (%) | 12/22 (55) | 6/80 (8) | < .001 |
| Increasing of cytotoxic T cells (%) | 11/17 (65) | 19/73 (26) | < .001 |
| Immunophenotype (%) | |||
| CD20 | 32/32 (100) | 19/99 (19) | < .001 |
| CD15 | 0/27 (0) | 64/106 (60) | < .001 |
| CD30 | 19/27 (70) | 99/107 (93) | .002 |
| CD45RO | 4/12 (33) | 1/77 (1) | .001 |
| CD56 | 0/13 (0) | 0/21 (0) | > .99 |
| EBER | 34/34 (100) | 108/108 (100) | > .99 |
| LMP1 | 29/29 (100) | 45/52 (87) | .039 |
| EBNA2 | 7/28 (25) | 0/24 (0) | .008 |
Values are indicated as number of positive/ tested cases.
EBV indicates Epstein-Barr virus; LPDs, lymphoproliferative disorders; and cHL, classic Hodgkin lymphoma.