Sequence analysis of antigen receptor rearrangements in sorted cell populations
| Patient no. and sample source . | Germline regions . | Junctional region . | |
|---|---|---|---|
| 7 | |||
| Diagnostic, unsorted | VH3-9*01/DH3-3/JH6*02 | −1/6/−14 | −9/3/−14 |
| CD133+CD19+ | VH3-9*01/DH3-3/JH6*02 | −1/6/−14 | −9/3/−14 |
| CD133+CD19− | VH3-9*01/DH3-3/JH6*02 | −1/6/−14 | −9/3/−14 |
| CD133−CD19+ | VH3-9*01/DH3-3/JH6*02 | −1/6/−14 | −9/3/−14 |
| CD133−CD19− | VH3-9*01/DH3-3/JH6*02 | −1/6/−14 | −9/3/−14 |
| 9 | |||
| Diagnostic, unsorted | VH2-5/DH2-2/JH6*02 | −1/8/−20 | −6/12/9 |
| CD133+CD19+ | VH2-5/DH2-2/JH6*02 | −1/8/−20 | −6/12/9 |
| CD133+CD19− | VH2-5/DH2-2/JH6*02 | −1/8/−20 | −6/12/9 |
| CD133−CD19+ | VH2-5/DH2-2/JH6*02 | −1/8/−20 | −6/12/9 |
| CD133−CD19− | † | ||
| 10 | |||
| Diagnostic, unsorted | VK3-20*01/Kde | 0/7/−6 | |
| CD133+CD19+ | VK3-20*01/Kde | 0/17/−23 | |
| VK3-20*01/Kde | 0/5/−11 | ||
| CD133+CD19− | VK3-20*01/Kde | 0/7/−6 | |
| CD133−CD19+ | VK3-20*01/Kde | 0/7/−6 | |
| CD133−CD19− | VK3-20*01/Kde | 0/7/−6 | |
| Diagnostic, unsorted | VK1-17*01/Kde | −1/0/−3 | |
| CD133+CD19+ | VK1-17*01/Kde | −1/0/−3 | |
| CD133+CD19− | VK1-17*01/Kde | −1/0/−3 | |
| CD133−CD19+ | VK1-17*01/Kde | 0/0/−24 | |
| CD133−CD19− | VK1-17*01/Kde | −1/0/−3 | |
| 14 | |||
| Diagnostic, unsorted | TCR G V9*01/TCR G J2*01 | −6/1/−1 | |
| CD133+CD19+ | TCR G V9*01/TCR G J2*01 | −6/1/−1 | |
| CD133+CD19− | TCR G V9*01/TCR G J2*01 | −6/1/−1 | |
| CD133−CD19+ | TCR G V9*01/TCR G J2*01 | −6/1/−1 | |
| CD133−CD19− | TCR G V9*01/TCR G J2*01 | −6/1/−1 | |
| Diagnostic, unsorted | TCR D V2*03/DD3 | 0/8/−23 | |
| CD133+CD19+ | TCR D V2*03/DD3 | 0/8/−23 | |
| CD133+CD19− | TCR D V2*03/DD3 | 0/8/−23 | |
| CD133−CD19+ | TCR D V2*03/DD3 | 0/8/−23 | |
| CD133−CD19− | TCR D V2*03/DD3 | 0/8/−23 | |
| 18 | |||
| Diagnostic, unsorted | VH1-3/DH2-15/JH5*02 | −13/12/−13 | −4/11/−4 |
| CD133+CD19+ | VH1-3/DH2-15/JH5*02 | −13/12/−13 | −4/11/−4 |
| CD133+CD19− | VH1-3/DH2-15/JH5*02 | −13/12/−13 | −4/11/−4 |
| CD133−CD19+ | VH1-3/DH2-15/JH5*02 | −13/12/−13 | −4/11/−4 |
| CD133−CD19− | VH1-3/DH2-15/JH5*02 | −13/12/−13 | −4/11/−4 |
| Diagnostic, unsorted | VH3-13*01/JH6*03 | 0/0/−6 | |
| CD133+CD19+ | VH3-13*01/JH6*03 | 0/0/−6 | |
| CD133+CD19− | VH3-13*01/JH6*03 | 0/0/−6 | |
| CD133−CD19+ | VH3-13*01/J4*02 | −1/18/−6 | |
| VH3-23*01/DH3-16*01/J6*03 | −2/12/−7 | −13/12/3 | |
| CD133−CD19− | VH3-13*01/JH6*03 | 0/0/−6 | |
| Patient no. and sample source . | Germline regions . | Junctional region . | |
|---|---|---|---|
| 7 | |||
| Diagnostic, unsorted | VH3-9*01/DH3-3/JH6*02 | −1/6/−14 | −9/3/−14 |
| CD133+CD19+ | VH3-9*01/DH3-3/JH6*02 | −1/6/−14 | −9/3/−14 |
| CD133+CD19− | VH3-9*01/DH3-3/JH6*02 | −1/6/−14 | −9/3/−14 |
| CD133−CD19+ | VH3-9*01/DH3-3/JH6*02 | −1/6/−14 | −9/3/−14 |
| CD133−CD19− | VH3-9*01/DH3-3/JH6*02 | −1/6/−14 | −9/3/−14 |
| 9 | |||
| Diagnostic, unsorted | VH2-5/DH2-2/JH6*02 | −1/8/−20 | −6/12/9 |
| CD133+CD19+ | VH2-5/DH2-2/JH6*02 | −1/8/−20 | −6/12/9 |
| CD133+CD19− | VH2-5/DH2-2/JH6*02 | −1/8/−20 | −6/12/9 |
| CD133−CD19+ | VH2-5/DH2-2/JH6*02 | −1/8/−20 | −6/12/9 |
| CD133−CD19− | † | ||
| 10 | |||
| Diagnostic, unsorted | VK3-20*01/Kde | 0/7/−6 | |
| CD133+CD19+ | VK3-20*01/Kde | 0/17/−23 | |
| VK3-20*01/Kde | 0/5/−11 | ||
| CD133+CD19− | VK3-20*01/Kde | 0/7/−6 | |
| CD133−CD19+ | VK3-20*01/Kde | 0/7/−6 | |
| CD133−CD19− | VK3-20*01/Kde | 0/7/−6 | |
| Diagnostic, unsorted | VK1-17*01/Kde | −1/0/−3 | |
| CD133+CD19+ | VK1-17*01/Kde | −1/0/−3 | |
| CD133+CD19− | VK1-17*01/Kde | −1/0/−3 | |
| CD133−CD19+ | VK1-17*01/Kde | 0/0/−24 | |
| CD133−CD19− | VK1-17*01/Kde | −1/0/−3 | |
| 14 | |||
| Diagnostic, unsorted | TCR G V9*01/TCR G J2*01 | −6/1/−1 | |
| CD133+CD19+ | TCR G V9*01/TCR G J2*01 | −6/1/−1 | |
| CD133+CD19− | TCR G V9*01/TCR G J2*01 | −6/1/−1 | |
| CD133−CD19+ | TCR G V9*01/TCR G J2*01 | −6/1/−1 | |
| CD133−CD19− | TCR G V9*01/TCR G J2*01 | −6/1/−1 | |
| Diagnostic, unsorted | TCR D V2*03/DD3 | 0/8/−23 | |
| CD133+CD19+ | TCR D V2*03/DD3 | 0/8/−23 | |
| CD133+CD19− | TCR D V2*03/DD3 | 0/8/−23 | |
| CD133−CD19+ | TCR D V2*03/DD3 | 0/8/−23 | |
| CD133−CD19− | TCR D V2*03/DD3 | 0/8/−23 | |
| 18 | |||
| Diagnostic, unsorted | VH1-3/DH2-15/JH5*02 | −13/12/−13 | −4/11/−4 |
| CD133+CD19+ | VH1-3/DH2-15/JH5*02 | −13/12/−13 | −4/11/−4 |
| CD133+CD19− | VH1-3/DH2-15/JH5*02 | −13/12/−13 | −4/11/−4 |
| CD133−CD19+ | VH1-3/DH2-15/JH5*02 | −13/12/−13 | −4/11/−4 |
| CD133−CD19− | VH1-3/DH2-15/JH5*02 | −13/12/−13 | −4/11/−4 |
| Diagnostic, unsorted | VH3-13*01/JH6*03 | 0/0/−6 | |
| CD133+CD19+ | VH3-13*01/JH6*03 | 0/0/−6 | |
| CD133+CD19− | VH3-13*01/JH6*03 | 0/0/−6 | |
| CD133−CD19+ | VH3-13*01/J4*02 | −1/18/−6 | |
| VH3-23*01/DH3-16*01/J6*03 | −2/12/−7 | −13/12/3 | |
| CD133−CD19− | VH3-13*01/JH6*03 | 0/0/−6 | |
Clonal rearrangement not present.