Table 2 Characteristics of HCV subjects... | American Society of Hematology

Table 2

Characteristics of HCV⁺ subjects

Subject no.	Sex	Age, y	HCV risk factor	HCV treatment status	ALT, IU/mL	HCV GT	HCV RNA, IU/mL × 10⁶	Stage	Extrahepatic conditions	Plasma [IgM RF], IU/mL	MC type
HCV⁺ MC⁻
108	M	57	IVDU	Naive	38	1	0.3	ND	Arthralgia	137.6	NA
159*	M	59	Unknown	NR	85	1a	10.1	3	Arthralgia	22.7	NA
162	M	51	IVDU	NR	46	1b	0.29	0	Arthralgia	8.5	NA
1087	M	58	IVDU	Naive	39	1	0.7	0	Arthralgia	13.6	NA
1148	F	48	Unknown	Naive	41	1a	10	2	NHL (in remission), neuropathy	6.4	NA
1235	F	41	Unknown	Naive	376	2b	3.9	ND	Arthralgia	4.0	NA
1330	F	54	IVDU	Naive	35	1a	10	2	Arthralgia, palpable purpura	8.3	NA
1339	M	58	IVDU	Naive	60	1	4.25	4	Arthralgia	6.6	NA
1345	M	57	IVDU	Naive	29	1a	0.3	ND	Arthralgia	6.7	NA
1349	F	53	Transfusion	Naive	27	2b	3.1	ND	Arthralgia	7.5	NA
1373	F	49	INDU	Relapser	29	1a	0.47	3	Palpable purpura	15.0	NA
1419	F	47	IVDU	Naive	23	1a	0.83	3	Arthralgia, palpable purpura	6.5	NA
1446	F	67	Transfusion	Naive	26	2b	0.6	0	Palpable purpura	60.9	NA
HCV⁺ MC⁺
192	M	55	Unknown	Naive	38	2b	0.66	1	Arthralgia, palpable purpura	10.0	III, IgMκ
389*	M	55	IVDU	NR	52	1a	2	3	Arthralgia, palpable purpura, neuropathy	7.5	II, IgMκ
734*	M	53	Unknown	Naive	117	1a	2.6	1	Arthralgia	32.6	ND
773*	F	29	Unknown	Naive	148	1b	0.38	4	Arthralgia, palpable purpura	68.8	II, IgMκ
880*	F	54	Unknown	Naive	40	1b	3.08	ND	Arthralgia, palpable purpura	46.2	II, IgMκ
960*	F	46	IVDU	Relapser	33	1a	4.2	2	Arthralgia	93.3	II, IgMκ
1073*	F	46	Unknown	NR	38	1a	1.34	2	Arthralgia, palpable purpura, neuropathy	37.0	II, IgMκ
1308*	F	54	IVDU	Naive	95	1a	0.7	1	NHL	237.5	II, IgMκ
1403*	F	47	IVDU	NR	13	1	1.34	4	Palpable purpura, GN, pulmonary hemorrhage	323.9	II, IgMκ
1432*	F	69	Transfusion	Relapser	56	1a	0.03	4	Palpable purpura, hemolytic anemia	35.2	II, IgMκ
11502	F	67	Transfusion	Naive	41	1a	0.11	2	Arthralgia	21.4	ND
92200*	F	57	Transfusion	Naive	ND	2b	3.1	2	Arthralgia, palpable purpura	5.3	III, IgMκ

Subject no.	Sex	Age, y	HCV risk factor	HCV treatment status	ALT, IU/mL	HCV GT	HCV RNA, IU/mL × 10⁶	Stage	Extrahepatic conditions	Plasma [IgM RF], IU/mL	MC type
HCV⁺ MC⁻
108	M	57	IVDU	Naive	38	1	0.3	ND	Arthralgia	137.6	NA
159*	M	59	Unknown	NR	85	1a	10.1	3	Arthralgia	22.7	NA
162	M	51	IVDU	NR	46	1b	0.29	0	Arthralgia	8.5	NA
1087	M	58	IVDU	Naive	39	1	0.7	0	Arthralgia	13.6	NA
1148	F	48	Unknown	Naive	41	1a	10	2	NHL (in remission), neuropathy	6.4	NA
1235	F	41	Unknown	Naive	376	2b	3.9	ND	Arthralgia	4.0	NA
1330	F	54	IVDU	Naive	35	1a	10	2	Arthralgia, palpable purpura	8.3	NA
1339	M	58	IVDU	Naive	60	1	4.25	4	Arthralgia	6.6	NA
1345	M	57	IVDU	Naive	29	1a	0.3	ND	Arthralgia	6.7	NA
1349	F	53	Transfusion	Naive	27	2b	3.1	ND	Arthralgia	7.5	NA
1373	F	49	INDU	Relapser	29	1a	0.47	3	Palpable purpura	15.0	NA
1419	F	47	IVDU	Naive	23	1a	0.83	3	Arthralgia, palpable purpura	6.5	NA
1446	F	67	Transfusion	Naive	26	2b	0.6	0	Palpable purpura	60.9	NA
HCV⁺ MC⁺
192	M	55	Unknown	Naive	38	2b	0.66	1	Arthralgia, palpable purpura	10.0	III, IgMκ
389*	M	55	IVDU	NR	52	1a	2	3	Arthralgia, palpable purpura, neuropathy	7.5	II, IgMκ
734*	M	53	Unknown	Naive	117	1a	2.6	1	Arthralgia	32.6	ND
773*	F	29	Unknown	Naive	148	1b	0.38	4	Arthralgia, palpable purpura	68.8	II, IgMκ
880*	F	54	Unknown	Naive	40	1b	3.08	ND	Arthralgia, palpable purpura	46.2	II, IgMκ
960*	F	46	IVDU	Relapser	33	1a	4.2	2	Arthralgia	93.3	II, IgMκ
1073*	F	46	Unknown	NR	38	1a	1.34	2	Arthralgia, palpable purpura, neuropathy	37.0	II, IgMκ
1308*	F	54	IVDU	Naive	95	1a	0.7	1	NHL	237.5	II, IgMκ
1403*	F	47	IVDU	NR	13	1	1.34	4	Palpable purpura, GN, pulmonary hemorrhage	323.9	II, IgMκ
1432*	F	69	Transfusion	Relapser	56	1a	0.03	4	Palpable purpura, hemolytic anemia	35.2	II, IgMκ
11502	F	67	Transfusion	Naive	41	1a	0.11	2	Arthralgia	21.4	ND
92200*	F	57	Transfusion	Naive	ND	2b	3.1	2	Arthralgia, palpable purpura	5.3	III, IgMκ

GT indicates genotype; IVDU, intravenous drug use; NA, not applicable; ND, not determined; NR, nonresponder; NHL, non-Hodgkin lymphoma; INDU, intranasal drug use; and GN, glomerulonephritis.

Subjects with clonal Ig (as determined by PBMC DNA CDR3 PCR).

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