Univariate analysis of the effect of risk factors on disease-free survival and overall survival in patients with acute myeloid leukemia
Variable . | Disease-free survival . | Overall survival . | ||
---|---|---|---|---|
No. of patients . | P . | No. of patients . | P . | |
Sex | .595 | .384 | ||
Male | 38 | 38 | ||
Female | 40 | 40 | ||
Age, y | .430 | .005* | ||
Younger than 50 | 41 | 41 | ||
Older than 50 | 37 | 37 | ||
Karyotype | .026* | .009* | ||
Favorable | 14 | 14 | ||
Intermediate | 52 | 52 | ||
Unfavorable | 10 | 10 | ||
WBC count, ×109/L | .875 | .915 | ||
Less than 30 | 55 | 55 | ||
30 or more | 23 | 23 | ||
LDH | .806 | .932 | ||
Less than 2× | 42 | 42 | ||
Greater than 2× | 36 | 36 | ||
Peak | .007* | .002* | ||
Low | 49 | 49 | ||
High | 29 | 29 | ||
Amp | .003* | .014* | ||
Low | 52 | 52 | ||
High | 26 | 26 | ||
K trans | .748 | .246 | ||
Low | 23 | 23 | ||
High | 55 | 55 |
Variable . | Disease-free survival . | Overall survival . | ||
---|---|---|---|---|
No. of patients . | P . | No. of patients . | P . | |
Sex | .595 | .384 | ||
Male | 38 | 38 | ||
Female | 40 | 40 | ||
Age, y | .430 | .005* | ||
Younger than 50 | 41 | 41 | ||
Older than 50 | 37 | 37 | ||
Karyotype | .026* | .009* | ||
Favorable | 14 | 14 | ||
Intermediate | 52 | 52 | ||
Unfavorable | 10 | 10 | ||
WBC count, ×109/L | .875 | .915 | ||
Less than 30 | 55 | 55 | ||
30 or more | 23 | 23 | ||
LDH | .806 | .932 | ||
Less than 2× | 42 | 42 | ||
Greater than 2× | 36 | 36 | ||
Peak | .007* | .002* | ||
Low | 49 | 49 | ||
High | 29 | 29 | ||
Amp | .003* | .014* | ||
Low | 52 | 52 | ||
High | 26 | 26 | ||
K trans | .748 | .246 | ||
Low | 23 | 23 | ||
High | 55 | 55 |
WBC indicates white blood cell; LDH, lactate dehydrogenase; 2×, 2 times normal range; Peak, peak enhancement ratio; Amp, amplitude; and K trans, volume transfer constant.
Relative risk that is statistically significant (P < .05).