Table 2

Univariate analysis of the effect of risk factors on disease-free survival and overall survival in patients with acute myeloid leukemia

VariableDisease-free survival
Overall survival
No. of patientsPNo. of patientsP
Sex  .595  .384 
    Male 38  38  
    Female 40  40  
Age, y  .430  .005* 
    Younger than 50 41  41  
    Older than 50 37  37  
Karyotype  .026*  .009* 
    Favorable 14  14  
    Intermediate 52  52  
    Unfavorable 10  10  
WBC count, ×109/L  .875  .915 
    Less than 30 55  55  
    30 or more 23  23  
LDH  .806  .932 
    Less than 2× 42  42  
    Greater than 2× 36  36  
Peak  .007*  .002* 
    Low 49  49  
    High 29  29  
Amp  .003*  .014* 
    Low 52  52  
    High 26  26  
K trans  .748  .246 
    Low 23  23  
    High 55  55  
VariableDisease-free survival
Overall survival
No. of patientsPNo. of patientsP
Sex  .595  .384 
    Male 38  38  
    Female 40  40  
Age, y  .430  .005* 
    Younger than 50 41  41  
    Older than 50 37  37  
Karyotype  .026*  .009* 
    Favorable 14  14  
    Intermediate 52  52  
    Unfavorable 10  10  
WBC count, ×109/L  .875  .915 
    Less than 30 55  55  
    30 or more 23  23  
LDH  .806  .932 
    Less than 2× 42  42  
    Greater than 2× 36  36  
Peak  .007*  .002* 
    Low 49  49  
    High 29  29  
Amp  .003*  .014* 
    Low 52  52  
    High 26  26  
K trans  .748  .246 
    Low 23  23  
    High 55  55  

WBC indicates white blood cell; LDH, lactate dehydrogenase; 2×, 2 times normal range; Peak, peak enhancement ratio; Amp, amplitude; and K trans, volume transfer constant.

*

Relative risk that is statistically significant (P < .05).

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