Table 2 ICP0 mutants ICP-0 mutant .... | American Society of Hematology

Table 2

ICP0 mutants

ICP-0 mutant	Deletion/mutation	Impact on ICP0 function
ICP0-M4	K620I	Loss of USP7 binding capacity
ICP0-FXE	Del of aa's 106-149	Deletion of E3 ligase RING domain
ICP0-NLS^mut	500-VRPRKRR-506 into 500-VRPAARA-506	Nuclear exclusion

ICP-0 mutant	Deletion/mutation	Impact on ICP0 function
ICP0-M4	K620I	Loss of USP7 binding capacity
ICP0-FXE	Del of aa's 106-149	Deletion of E3 ligase RING domain
ICP0-NLS^mut	500-VRPRKRR-506 into 500-VRPAARA-506	Nuclear exclusion