Table 2

Tetramer staining of the 10 vaccinated patients in this trial

Patient no.Before first vaccinationAfter first vaccinationAfter second vaccinationAfter third vaccinationAfter fourth vaccinationImmune response
1 0.05 nt 0.03 0.06 0.11 Positive 
2 0.54 0.46 0.51 0.73 0.63 Positive 
3 0.46 0.65 0.42 0.7 nt Positive 
4 0.48 nt 0.48 0.52 nt No change 
5 nt nt nt nt nt nt 
6 0.33 0.28 0.29 0.42 0.31 Positive 
7 0.16 0.13 0.16 0.15 0.13 No change 
8 0.55 0.41 0.40 1.23 0.46 Positive 
9 0.06 0.14 0.13 0.09 0.11 Positive 
10 0.28 0.53 0.47 0.38 0.56 Positive 
Patient no.Before first vaccinationAfter first vaccinationAfter second vaccinationAfter third vaccinationAfter fourth vaccinationImmune response
1 0.05 nt 0.03 0.06 0.11 Positive 
2 0.54 0.46 0.51 0.73 0.63 Positive 
3 0.46 0.65 0.42 0.7 nt Positive 
4 0.48 nt 0.48 0.52 nt No change 
5 nt nt nt nt nt nt 
6 0.33 0.28 0.29 0.42 0.31 Positive 
7 0.16 0.13 0.16 0.15 0.13 No change 
8 0.55 0.41 0.40 1.23 0.46 Positive 
9 0.06 0.14 0.13 0.09 0.11 Positive 
10 0.28 0.53 0.47 0.38 0.56 Positive 

Immune response: an initial value less than 0.1% was judged positive if there was a consecutive increase more than 50%; an initial value more than 0.1% was judged positive if there was a consecutive increase more than 25%.

nt indicates not tested, that is, not sufficient cells for tetramer staining (apart from ELISpot assays).

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