Clinical characteristics of all patients with WR-NKTL and comparison of clinical characteristics between nasopharyngeal and tonsil NK/T-cell lymphoma
Characteristic . | All patients, n = 91, no. (%) . | Nasopharynx, n = 52, no. (%) . | Tonsil, n = 35, no. (%) . | Nasopharynx vs tonsil, P value . |
---|---|---|---|---|
Sex | ||||
Male | 66 (73) | 37 (71) | 26 (74) | |
Female | 25 (27) | 15 (29) | 9 (26) | .729 |
Age | ||||
Median | 37 | 37 | 42 | |
Range | 7-79 | 9-79 | 7-69 | |
60 y or younger | 81 (89) | 47 (90) | 31 (89) | |
Older than 60 y | 10 (11) | 5 (10) | 4 (11) | .785 |
Ann Arbor stage | ||||
I | 15 (16) | 9 (17) | 5 (14) | |
II | 56 (62) | 34 (65) | 19 (54) | |
III | 12 (13) | 5 (10) | 7 (20) | |
IV | 8 (9) | 4 (8) | 4 (11) | .476 |
Nodal involvement | ||||
Present | 75 (82) | 39 (75) | 28 (80) | |
Absent | 16 (18) | 13 (25) | 7 (20) | .587 |
Involvement of adjacent organs or tissues | ||||
Present | 54 (59) | 44 (85) | 8 (23) | |
Absent | 37 (41) | 8 (15) | 27 (77) | .000 |
B symptoms | 30 (33) | 23 (44) | 6 (17) | .011 |
Elevated LDH level | 16 (18) | 10 (19) | 6 (17) | .781 |
ECOG score | ||||
0 | 23 (25) | 15 (29) | 7 (20) | |
1 | 65 (71) | 35 (67) | 27 (77) | |
2 | 3 (3) | 2 (4) | 1 (3) | .609 |
IPI | ||||
0 | 53 (58) | 33 (63) | 17 (49) | |
1 | 25 (28) | 13 (25) | 11 (31) | |
2 | 9 (10) | 4 (8) | 5 (14) | |
3 | 2 (2) | 1 (2) | 1 (3) | |
4 | 2 (2) | 1 (2) | 1 (3) | .707 |
Characteristic . | All patients, n = 91, no. (%) . | Nasopharynx, n = 52, no. (%) . | Tonsil, n = 35, no. (%) . | Nasopharynx vs tonsil, P value . |
---|---|---|---|---|
Sex | ||||
Male | 66 (73) | 37 (71) | 26 (74) | |
Female | 25 (27) | 15 (29) | 9 (26) | .729 |
Age | ||||
Median | 37 | 37 | 42 | |
Range | 7-79 | 9-79 | 7-69 | |
60 y or younger | 81 (89) | 47 (90) | 31 (89) | |
Older than 60 y | 10 (11) | 5 (10) | 4 (11) | .785 |
Ann Arbor stage | ||||
I | 15 (16) | 9 (17) | 5 (14) | |
II | 56 (62) | 34 (65) | 19 (54) | |
III | 12 (13) | 5 (10) | 7 (20) | |
IV | 8 (9) | 4 (8) | 4 (11) | .476 |
Nodal involvement | ||||
Present | 75 (82) | 39 (75) | 28 (80) | |
Absent | 16 (18) | 13 (25) | 7 (20) | .587 |
Involvement of adjacent organs or tissues | ||||
Present | 54 (59) | 44 (85) | 8 (23) | |
Absent | 37 (41) | 8 (15) | 27 (77) | .000 |
B symptoms | 30 (33) | 23 (44) | 6 (17) | .011 |
Elevated LDH level | 16 (18) | 10 (19) | 6 (17) | .781 |
ECOG score | ||||
0 | 23 (25) | 15 (29) | 7 (20) | |
1 | 65 (71) | 35 (67) | 27 (77) | |
2 | 3 (3) | 2 (4) | 1 (3) | .609 |
IPI | ||||
0 | 53 (58) | 33 (63) | 17 (49) | |
1 | 25 (28) | 13 (25) | 11 (31) | |
2 | 9 (10) | 4 (8) | 5 (14) | |
3 | 2 (2) | 1 (2) | 1 (3) | |
4 | 2 (2) | 1 (2) | 1 (3) | .707 |
WR-NKTL indicates nasal-type NK/T-cell lymphoma of Waldeyer ring; LDH, lactate dehydrogenase; ECOG, Eastern Cooperative Oncology Group; and IPI, international prognostic index.