Best observed cytogenetic response and long-term outcomes with imatinib by prior outcome with IFN
| Prior outcome on IFN . | No. of patients . | % Best observed cytogenetic response rate with imatinib . | Estimated % rate (Kaplan-Meier) at 6 y with imatinib . | ||
|---|---|---|---|---|---|
| MCyR . | CCyR . | PFS . | Survival . | ||
| Hematologic failure | 133 | 57 | 48 | 51 | 73 |
| Cytogenetic failure | 160 | 71 | 60 | 68 | 81 |
| Intolerance | 161 | 72 | 61 | 62 | 73 |
| Overall | 454 | 67 | 57 | 61 | 76 |
| Prior outcome on IFN . | No. of patients . | % Best observed cytogenetic response rate with imatinib . | Estimated % rate (Kaplan-Meier) at 6 y with imatinib . | ||
|---|---|---|---|---|---|
| MCyR . | CCyR . | PFS . | Survival . | ||
| Hematologic failure | 133 | 57 | 48 | 51 | 73 |
| Cytogenetic failure | 160 | 71 | 60 | 68 | 81 |
| Intolerance | 161 | 72 | 61 | 62 | 73 |
| Overall | 454 | 67 | 57 | 61 | 76 |