Main baseline characteristics of included patients
| . | No. (%) or median (Q1-Q3) . |
|---|---|
| No. of patients | 37 |
| Age at diagnosis, y | 49 (42-53) |
| Male sex | 16, 43% |
| Splenomegaly | 13/37 (35%) |
| Spleen enlargement below costal margin (in cm, in 7 patients with palpable splenomegaly) | 2 (2-2) |
| Spleen size by ultrasound (in cm, in 6 patients with splenomegaly by imaging) | 14 (13.2-14) |
| Time since diagnosis, mo | 5 (1-11) |
| History of major thrombosis | 5 (14%) |
| Patients with previous phlebotomies | 20 (54%) |
| No. of phlebotomies in the past 3 mo* | 3 (3-5) |
| Previously on HU | 12 (32%) |
| Hematocrit,† % | 51 (49-56.5) |
| Hemoglobin,† g/dL | 16.9 (15.6-19.2) |
| Leukocytes,† ×109/L | 10.0 (7.3-13.4) |
| ANC,† ×109/L | 7.3 (5.9-10) |
| Platelets,† ×109/L | 720 (471-910) |
| JAK2V617F positive | 29 (83%) |
| %V617F | 45 (35-60) |
| . | No. (%) or median (Q1-Q3) . |
|---|---|
| No. of patients | 37 |
| Age at diagnosis, y | 49 (42-53) |
| Male sex | 16, 43% |
| Splenomegaly | 13/37 (35%) |
| Spleen enlargement below costal margin (in cm, in 7 patients with palpable splenomegaly) | 2 (2-2) |
| Spleen size by ultrasound (in cm, in 6 patients with splenomegaly by imaging) | 14 (13.2-14) |
| Time since diagnosis, mo | 5 (1-11) |
| History of major thrombosis | 5 (14%) |
| Patients with previous phlebotomies | 20 (54%) |
| No. of phlebotomies in the past 3 mo* | 3 (3-5) |
| Previously on HU | 12 (32%) |
| Hematocrit,† % | 51 (49-56.5) |
| Hemoglobin,† g/dL | 16.9 (15.6-19.2) |
| Leukocytes,† ×109/L | 10.0 (7.3-13.4) |
| ANC,† ×109/L | 7.3 (5.9-10) |
| Platelets,† ×109/L | 720 (471-910) |
| JAK2V617F positive | 29 (83%) |
| %V617F | 45 (35-60) |