Baseline patient characteristics
Characteristic . | No. (%) . |
---|---|
Total patients in analysis | 1514 |
Age, y | |
Mean | 45 |
Standard deviation | 12 |
Sex | |
Male | 769 (51) |
Female | 745 (49) |
Race | |
White | 1311 (87) |
Black | 155 (10) |
Other | 48 (3) |
Disease category | |
Hematologic malignancy | 1291 (85) |
Solid tumor | 223 (15) |
Diagnosis | |
Hematologic malignancies | |
Non-Hodgkin lymphoma | 508 (34) |
Acute myeloid leukemia | 219 (14) |
Multiple myeloma | 147 (10) |
Hodgkin disease | 138 (9) |
Chronic myeloid leukemia | 114 (8) |
Acute lymphocytic leukemia | 59 (4) |
Myelodysplastic syndrome | 47 (3) |
Chronic lymphocytic leukemia | 37 (2) |
Aplastic anemia | 20 (1) |
Other | 2 (<1) |
Solid tumors | |
Breast | 191 (13) |
Ovarian | 23 (2) |
Other | 9 (<1) |
Type of transplantation | |
Autologous | 928 (61) |
Allogeneic | 586 (39) |
Conditioning regimen | |
Busulfan-cyclophosphamide | 830 (55) |
Cyclophosphamide-total body irradiation | 397 (26) |
Cyclophosphamide-thiotepa | 191 (13) |
Carboplatin-based | 32 (2) |
Cyclophosphamide | 16 (1) |
Melphalan | 9 (1) |
Other | 5 (<1) |
Unknown | 34 (2) |
Duration of hospitalization, d | |
Median | 26 |
IQR 25 to 75 | 21-36 |
Vital status at discharge | |
Alive | 1384 (91) |
Dead | 130 (9) |
Overall survival after transplantation, d | |
Median | 269 |
IQR | 86-826 |
Complications of transplantation | |
Graft-versus-host disease | 300 (20) |
Veno-occlusive disease | 99 (7) |
Cytomegalovirus | 86 (6) |
Immune modulators | |
Cyclosporine | 673 (44) |
Corticosteroids | 293 (19) |
Characteristic . | No. (%) . |
---|---|
Total patients in analysis | 1514 |
Age, y | |
Mean | 45 |
Standard deviation | 12 |
Sex | |
Male | 769 (51) |
Female | 745 (49) |
Race | |
White | 1311 (87) |
Black | 155 (10) |
Other | 48 (3) |
Disease category | |
Hematologic malignancy | 1291 (85) |
Solid tumor | 223 (15) |
Diagnosis | |
Hematologic malignancies | |
Non-Hodgkin lymphoma | 508 (34) |
Acute myeloid leukemia | 219 (14) |
Multiple myeloma | 147 (10) |
Hodgkin disease | 138 (9) |
Chronic myeloid leukemia | 114 (8) |
Acute lymphocytic leukemia | 59 (4) |
Myelodysplastic syndrome | 47 (3) |
Chronic lymphocytic leukemia | 37 (2) |
Aplastic anemia | 20 (1) |
Other | 2 (<1) |
Solid tumors | |
Breast | 191 (13) |
Ovarian | 23 (2) |
Other | 9 (<1) |
Type of transplantation | |
Autologous | 928 (61) |
Allogeneic | 586 (39) |
Conditioning regimen | |
Busulfan-cyclophosphamide | 830 (55) |
Cyclophosphamide-total body irradiation | 397 (26) |
Cyclophosphamide-thiotepa | 191 (13) |
Carboplatin-based | 32 (2) |
Cyclophosphamide | 16 (1) |
Melphalan | 9 (1) |
Other | 5 (<1) |
Unknown | 34 (2) |
Duration of hospitalization, d | |
Median | 26 |
IQR 25 to 75 | 21-36 |
Vital status at discharge | |
Alive | 1384 (91) |
Dead | 130 (9) |
Overall survival after transplantation, d | |
Median | 269 |
IQR | 86-826 |
Complications of transplantation | |
Graft-versus-host disease | 300 (20) |
Veno-occlusive disease | 99 (7) |
Cytomegalovirus | 86 (6) |
Immune modulators | |
Cyclosporine | 673 (44) |
Corticosteroids | 293 (19) |
IQR indicates interquartile range.