AUC for ELISPOT and CFC assays
| Assay . | Cohort 0, n = 13 . | Cohort 1, n = 5 . | Cohort 2, n = 5 . |
|---|---|---|---|
| ELISPOT, median (range) | 177.98 (29.37-610.48) | 317.43 (76.12-780.8) | 532.05 (207.74-667.39) |
| CFC percentage of CD4, median (range) | 3.37 (1.28-8.17) | 3.8 (1.8-8.19) | 4.26 (3.02-13.16) |
| CFC percentage of CD8, median (range) | 6.03 (1.33-13.47) | 7.04 (2.81-9.63) | 13.25 (5.0-15.16) |
| Assay . | Cohort 0, n = 13 . | Cohort 1, n = 5 . | Cohort 2, n = 5 . |
|---|---|---|---|
| ELISPOT, median (range) | 177.98 (29.37-610.48) | 317.43 (76.12-780.8) | 532.05 (207.74-667.39) |
| CFC percentage of CD4, median (range) | 3.37 (1.28-8.17) | 3.8 (1.8-8.19) | 4.26 (3.02-13.16) |
| CFC percentage of CD8, median (range) | 6.03 (1.33-13.47) | 7.04 (2.81-9.63) | 13.25 (5.0-15.16) |
AUCs were computed based on ELISPOT measurements denoted as spots per 100 000 PBMCs times weeks and based on percentage of cytokine-secreting cells times weeks for the cytokine flow cytometry (CFC) assay.