Table 3 Serum chemistries in the... | American Society of Hematology

Table 3

Serum chemistries in the AAV-treated hemophilia dogs

Day	CPK 59-895 U/L	AP 5-131 U/L	SGPT 12-118 U/L	SGOT 15-66 U/L	Total bilirubin 0.1-0.3 mg/dL	GGTP 1.0-12 U/L
HB-1-J10 dog
Baseline	340	134	37	33	0.1	< 5
3	344	163	101	27	0.1	< 5
14	283	136	32	27	0.1	< 5
108	253	67	46	25	0.1	< 5
297	145	45	45	23	0.2	< 5
358	87	25	40	24	0.1	< 5
527	104	32	36	19	0.3	< 5
HB-1-J10 dog
Baseline	13	79	28	32	0.1	< 5
3	207	81	65	37	0.2	< 5
93	133	48	72	41	0.2	< 5
296	80	44	41	31	0.2	< 5
435	100	29	71	31	0.2	< 5
HA-2-J57 dog
Baseline	100	46	34	35	0.2	< 5
3	103	91	46	22	0.2	< 5
86	116	41	47	44	0.2	< 5
275	80	22	31	24	0.2	< 5
470	107	41	47	27	0.3	< 5
554	131	33	87	35	0.2	< 5
HA-3-E66 dog
Baseline	152	20	73	45	0.1	< 5
3	243	47	98	49	0.1	< 5
6	177	41	68	36	0.1	< 5
105	131	15	55	33	0.1	< 5
301	153	15	44	32	0.1	< 5
365	93	16	53	34	0.1	< 5

Day	CPK 59-895 U/L	AP 5-131 U/L	SGPT 12-118 U/L	SGOT 15-66 U/L	Total bilirubin 0.1-0.3 mg/dL	GGTP 1.0-12 U/L
HB-1-J10 dog
Baseline	340	134	37	33	0.1	< 5
3	344	163	101	27	0.1	< 5
14	283	136	32	27	0.1	< 5
108	253	67	46	25	0.1	< 5
297	145	45	45	23	0.2	< 5
358	87	25	40	24	0.1	< 5
527	104	32	36	19	0.3	< 5
HB-1-J10 dog
Baseline	13	79	28	32	0.1	< 5
3	207	81	65	37	0.2	< 5
93	133	48	72	41	0.2	< 5
296	80	44	41	31	0.2	< 5
435	100	29	71	31	0.2	< 5
HA-2-J57 dog
Baseline	100	46	34	35	0.2	< 5
3	103	91	46	22	0.2	< 5
86	116	41	47	44	0.2	< 5
275	80	22	31	24	0.2	< 5
470	107	41	47	27	0.3	< 5
554	131	33	87	35	0.2	< 5
HA-3-E66 dog
Baseline	152	20	73	45	0.1	< 5
3	243	47	98	49	0.1	< 5
6	177	41	68	36	0.1	< 5
105	131	15	55	33	0.1	< 5
301	153	15	44	32	0.1	< 5
365	93	16	53	34	0.1	< 5

The normal range (derived from 18 clinically healthy dogs) is stated for each test. CPK indicates creatine phosphokinase; AP, alkaline phosphatase; SGPT, serum glutamic pyruvic transaminase; SGOT, serum glutamic oxaloacetic transaminase; and GGPT, gamma glutamyl transpeptidase.

View Large

This Feature Is Available To Subscribers Only