Excess mortality ratios and 95% CIs during first 5 years after AML diagnosis by calendar period, sex, region of residency, and age at diagnosis
| . | Excess mortality ratio . | 95% CI . | P . |
|---|---|---|---|
| Calendar period of AML diagnosis | |||
| 1973-1980 | 1.00 (reference) | ||
| 1981-1988 | 0.77 | 0.73, 0.83 | < .001 |
| 1989-1996 | 0.50 | 0.47, 0.54 | < .001 |
| 1997-2005 | 0.44 | 0.42, 0.47 | < .001 |
| Sex | |||
| Male | 1.00 (reference) | ||
| Female | 0.95 | 0.91, 0.996 | .032 |
| Region of residency | |||
| LGMS | 0.94 | 0.90, 0.98 | .006 |
| Other | 1.00 (reference) | ||
| Age at AML diagnosis, y | |||
| 0-18 | 1.00 (reference) | ||
| 19-40 | 1.26 | 1.08, 1.46 | .003 |
| 41-60 | 1.80 | 1.57, 2.07 | < .001 |
| 61-70 | 2.72 | 2.38, 3.11 | < .001 |
| 71-80 | 4.71 | 4.12, 5.37 | < .001 |
| Older than 80 | 7.62 | 6.64, 8.74 | < .001 |
| Prior MDS* | |||
| No | 1.00 (reference) | ||
| Yes | 1.51 | 1.31, 1.74 | < .001 |
| . | Excess mortality ratio . | 95% CI . | P . |
|---|---|---|---|
| Calendar period of AML diagnosis | |||
| 1973-1980 | 1.00 (reference) | ||
| 1981-1988 | 0.77 | 0.73, 0.83 | < .001 |
| 1989-1996 | 0.50 | 0.47, 0.54 | < .001 |
| 1997-2005 | 0.44 | 0.42, 0.47 | < .001 |
| Sex | |||
| Male | 1.00 (reference) | ||
| Female | 0.95 | 0.91, 0.996 | .032 |
| Region of residency | |||
| LGMS | 0.94 | 0.90, 0.98 | .006 |
| Other | 1.00 (reference) | ||
| Age at AML diagnosis, y | |||
| 0-18 | 1.00 (reference) | ||
| 19-40 | 1.26 | 1.08, 1.46 | .003 |
| 41-60 | 1.80 | 1.57, 2.07 | < .001 |
| 61-70 | 2.72 | 2.38, 3.11 | < .001 |
| 71-80 | 4.71 | 4.12, 5.37 | < .001 |
| Older than 80 | 7.62 | 6.64, 8.74 | < .001 |
| Prior MDS* | |||
| No | 1.00 (reference) | ||
| Yes | 1.51 | 1.31, 1.74 | < .001 |
All variables are simultaneously adjusted for all other variables in the table, excluding prior MDS diagnosis.
Analyzed on patients diagnosed 1993-2005 only, adjusted for all other variables in the table.