Table 5

Median, 2-, 5-, and 10-year (predicted) overall survivals

CharacteristicnMedian survival, mo2 years, %5 years, %10 years, %
Estimated overall survival (entire cohort) 
    From diagnosis of advanced-stage disease 92 60 65.8 48.9 31.8 
Clinical stage (P < .003) 
    Stage IIB 42 36 61.0 39.4 23.4 
    Stage III 36 132 83.9 67.8 53.9 
    Stages IVA and IVB 12 14.5 25 12.5 — 
Tumor (T) stage (P = .01) 
    Patch/plaque (T2) 42.9 21.4 — 
    Tumor (T3) 46 29 55.7 36.7 21.8 
    Erythroderma (T4) 39 132 82.9 65.2 52.3 
Presentation (P = .25) 
    Advanced-stage de novo 62 61 72.3 53.0 32.1 
    Progression from early-stage 30 36 51.9 41.5 34.6 
Age at initial diagnosis (P = .01) 
    60 y or older 47 72 75.1 57.4 26.1 
    Younger than 60 y 45 144 86.1 72.5 55.9 
Large cell transformation (P = .17) 
    No transformation 70 62 70.7 53.6 34.0 
    Transformation 22 27 50.6 32.5 — 
CD30 large cell expression (P = .19) 
    CD30-positive large cells 57 55.6 41.7 — 
    CD30-negative large cells 13 27 51.9 — — 
Erythrodermic disease (P = .34) 
    Sézary syndrome 31 132 75.0 60.8 54.7 
    Erythrodermic mycosis fungoides 96 100.0 50.0 — 
CharacteristicnMedian survival, mo2 years, %5 years, %10 years, %
Estimated overall survival (entire cohort) 
    From diagnosis of advanced-stage disease 92 60 65.8 48.9 31.8 
Clinical stage (P < .003) 
    Stage IIB 42 36 61.0 39.4 23.4 
    Stage III 36 132 83.9 67.8 53.9 
    Stages IVA and IVB 12 14.5 25 12.5 — 
Tumor (T) stage (P = .01) 
    Patch/plaque (T2) 42.9 21.4 — 
    Tumor (T3) 46 29 55.7 36.7 21.8 
    Erythroderma (T4) 39 132 82.9 65.2 52.3 
Presentation (P = .25) 
    Advanced-stage de novo 62 61 72.3 53.0 32.1 
    Progression from early-stage 30 36 51.9 41.5 34.6 
Age at initial diagnosis (P = .01) 
    60 y or older 47 72 75.1 57.4 26.1 
    Younger than 60 y 45 144 86.1 72.5 55.9 
Large cell transformation (P = .17) 
    No transformation 70 62 70.7 53.6 34.0 
    Transformation 22 27 50.6 32.5 — 
CD30 large cell expression (P = .19) 
    CD30-positive large cells 57 55.6 41.7 — 
    CD30-negative large cells 13 27 51.9 — — 
Erythrodermic disease (P = .34) 
    Sézary syndrome 31 132 75.0 60.8 54.7 
    Erythrodermic mycosis fungoides 96 100.0 50.0 — 

— indicates not applicable.

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