Table 2 Flow cytometric aberrancies in... | American Society of Hematology

Table 2

Flow cytometric aberrancies in myeloid blasts, granulocytes, and monocytes

Myeloid blasts	Granulocytes (maturing myeloid cells)	Monocytes
Increased percentage	Decreased myeloid-lymphoid ratio (< 1)	Decreased/increased number compared with lymphocytes
Abnormal granularity*	Abnormal granularity*	Abnormal granularity*
Abnormal expression† of CD45	Abnormal expression of CD45	Abnormal expression of CD45
Abnormal expression of CD34	Abnormal CD11b/CD13 pattern	Abnormal expression of CD14
Abnormal expression of CD117	Abnormal CD16/CD13 pattern	Abnormal CD11b/HLA-DR pattern
Abnormal expression of CD13	Abnormal expression of CD15	Abnormal expression of CD13
Abnormal expression of CD33	Abnormal expression of CD33	Abnormal expression of CD33
Abnormal expression of HLA-DR	Expression of HLA-DR	Abnormal expression of CD36
Expression of CD11b	Expression of CD34	Abnormal expression of HLA-DR
Expression of CD15	Asynchronous shift to the left	Expression of CD34
Expression of lineage infidelity markers CD5, CD7, CD19, or CD56	Expression of lineage infidelity markers CD5, CD7, CD19	Expression of lineage infidelity markers CD5, CD7, CD19
Expression of lineage infidelity markers CD5, CD7, CD19, or CD56	Overexpression of CD56	Overexpression of CD56

Myeloid blasts	Granulocytes (maturing myeloid cells)	Monocytes
Increased percentage	Decreased myeloid-lymphoid ratio (< 1)	Decreased/increased number compared with lymphocytes
Abnormal granularity*	Abnormal granularity*	Abnormal granularity*
Abnormal expression† of CD45	Abnormal expression of CD45	Abnormal expression of CD45
Abnormal expression of CD34	Abnormal CD11b/CD13 pattern	Abnormal expression of CD14
Abnormal expression of CD117	Abnormal CD16/CD13 pattern	Abnormal CD11b/HLA-DR pattern
Abnormal expression of CD13	Abnormal expression of CD15	Abnormal expression of CD13
Abnormal expression of CD33	Abnormal expression of CD33	Abnormal expression of CD33
Abnormal expression of HLA-DR	Expression of HLA-DR	Abnormal expression of CD36
Expression of CD11b	Expression of CD34	Abnormal expression of HLA-DR
Expression of CD15	Asynchronous shift to the left	Expression of CD34
Expression of lineage infidelity markers CD5, CD7, CD19, or CD56	Expression of lineage infidelity markers CD5, CD7, CD19	Expression of lineage infidelity markers CD5, CD7, CD19
Expression of lineage infidelity markers CD5, CD7, CD19, or CD56	Overexpression of CD56	Overexpression of CD56

Granularity was expressed as SSC of a specific subpopulation compared with the SSC of the lymphocytes.

Abnormal expression can either be lack of expression, underexpression, or overexpression of a certain antigen.