Combinations of NOTCH1 mutations HD (heterodimerization) and PEST (proline, glutamatic acid, serine, threonine), and FBXW7 mutations
| NOTCH1/FBXW7 mutation . | HD only, n (%) . | HD + PEST, n (%) . | PEST only, n (%) . | Others, n (%) . |
|---|---|---|---|---|
| GL | 41 (29) | 13 (9) | 9 (6) | 4* (3) |
| Mutated | 18 (13) | 2 (1) | 0 (0) | 1† (1) |
| Total | 59 (42) | 15 (10) | 9 (6) | 5 (4) |