Table 1 Reactions of selected mAbs with... | American Society of Hematology

Table 1

Reactions of selected mAbs with wild-type and mutant GPIIb*

Target construct	Monoclonal
Target construct	313.4	314.3	10E5	312.6	312.8
Wild-type GPIIb	+	+	+	+	+
GPIIbR1-144H	–	–	+	+	+
GPIIbR1-246H	–	–	–	+	–

Target construct	Monoclonal
Target construct	313.4	314.3	10E5	312.6	312.8
Wild-type GPIIb	+	+	+	+	+
GPIIbR1-144H	–	–	+	+	+
GPIIbR1-246H	–	–	–	+	–

GPIIb was coexpressed in CHO cells with wild-type human GPIIIa.