Comparison of responses after S-HAM in the AML-CG 2004 study and standard double induction in the AML-CG 1999 study in de novo AML according to age and cytogenetics
| . | ORR, % . | PL, % . | ED, % . | |||
|---|---|---|---|---|---|---|
| 1999 . | 2004 . | 1999 . | 2004 . | 1999 . | 2004 . | |
| Age | ||||||
| < 60 y | 72 | 82 | 11 | 7 | 17 | 11 |
| ≥ 60 y | 59 | 85 | 15 | 7 | 26 | 7 |
| Cytogenetics | ||||||
| Favorable | 74 | 93 | 6 | 0 | 20 | 7 |
| Intermediate | 71 | 88 | 12 | 5 | 17 | 7 |
| Unfavorable | 45 | 70 | 25 | 18 | 30 | 12 |
| . | ORR, % . | PL, % . | ED, % . | |||
|---|---|---|---|---|---|---|
| 1999 . | 2004 . | 1999 . | 2004 . | 1999 . | 2004 . | |
| Age | ||||||
| < 60 y | 72 | 82 | 11 | 7 | 17 | 11 |
| ≥ 60 y | 59 | 85 | 15 | 7 | 26 | 7 |
| Cytogenetics | ||||||
| Favorable | 74 | 93 | 6 | 0 | 20 | 7 |
| Intermediate | 71 | 88 | 12 | 5 | 17 | 7 |
| Unfavorable | 45 | 70 | 25 | 18 | 30 | 12 |
ORR indicates overall response rate; PL, persistent leukemia; and ED, early death.