Table 1 Iron binding parameters of... | American Society of Hematology

Table 1

Iron binding parameters of agents used in this study

Iron ligands (abbreviations)	pFe(III)*
Calcein green (CALG)	20.3†
Deferrioxamine (DFO)	26.6
Deferiprone (DFP)	19.3
Diethylene-triamine-pentaacetic acid (DTPA)	28.2
Nitrilotriacetic acid (NTA)	18.1
Transferrin (Tf)	22.3
Rhodamine B-[(1, 10-phenanthrolin-5-yl) aminocarbonyl] benzyl ester (RPA)	7.7 (11.5 for Fe(II))‡

Iron ligands (abbreviations)	pFe(III)*
Calcein green (CALG)	20.3†
Deferrioxamine (DFO)	26.6
Deferiprone (DFP)	19.3
Diethylene-triamine-pentaacetic acid (DTPA)	28.2
Nitrilotriacetic acid (NTA)	18.1
Transferrin (Tf)	22.3
Rhodamine B-[(1, 10-phenanthrolin-5-yl) aminocarbonyl] benzyl ester (RPA)	7.7 (11.5 for Fe(II))‡

pFe(III) values are −log[M], where M is the concentration of the free metal ion when [ligand] = 10μM and [Fe(III)] = 1μM at pH 7.4. Data from Harris.¹⁷

†

Data from Thomas et al.¹⁸

‡

Values shown are for 1,10-phenanthroline.

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