Table 1

Pretreatment characteristics of the 47 patients treated with lenalidomide

CharacteristicValue
Age, y, median (range) 69 (36-84) 
Sex, female/male 23/24 
Diagnosis according to WHO  
    Pure RA 2 (4%) 
    RCMD-RS 1 (2%) 
    RAEB-1 6 (13%) 
    RAEB-2 20 (43%) 
    AML (RAEB-T according to FAB classification) 18 (38%) 
IPSS score  
    Int-2 28 (60%) 
    High 19 (40%) 
Cytogenetics  
    Isolated del 5q 9 (19%) 
    del 5q and 1 additional abnormality 11 (23%) 
    del 5q with 2 or more additional abnormalities 27 (58%) 
RBC transfusion requirement 43/47 (91%) 
ANC < 1000/mm3 18/47 (38%) 
Platelets < 100 000/mm3 27/47 (57%) 
Bone marrow blasts > 10% 37/47 (78%) 
CharacteristicValue
Age, y, median (range) 69 (36-84) 
Sex, female/male 23/24 
Diagnosis according to WHO  
    Pure RA 2 (4%) 
    RCMD-RS 1 (2%) 
    RAEB-1 6 (13%) 
    RAEB-2 20 (43%) 
    AML (RAEB-T according to FAB classification) 18 (38%) 
IPSS score  
    Int-2 28 (60%) 
    High 19 (40%) 
Cytogenetics  
    Isolated del 5q 9 (19%) 
    del 5q and 1 additional abnormality 11 (23%) 
    del 5q with 2 or more additional abnormalities 27 (58%) 
RBC transfusion requirement 43/47 (91%) 
ANC < 1000/mm3 18/47 (38%) 
Platelets < 100 000/mm3 27/47 (57%) 
Bone marrow blasts > 10% 37/47 (78%) 
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