Cell surface marker expression of human BM-derived ALDHlo and ALDHhi cells
| Cell type . | Hematopoietic . | Progenitor . | Endothelial . | |||||
|---|---|---|---|---|---|---|---|---|
| CD45 (%) . | CD3 (%) . | CD19 (%) . | CD14 (%) . | CD34 (%) . | CD133 (%) . | CD117 (%) . | CD144 (%) . | |
| ALDHlo | 98.5 ± 1.4* | 75.3 ± 5.3† | 15.4 ± 2.3* | 2.6 ± 0.8 | 1.0 ± 0.4 | 1.6 ± 0.6 | 4.7 ± 1.4 | 2.6 ± 0.4 |
| ALDHhi | 88.9 ± 5.8 | 6.2 ± 2.5 | 4.4 ± 2.1 | 12.0 ± 3.5* | 50.2 ± 1.8† | 51.7 ± 7.6† | 74.9 ± 7.5† | 8.9 ± 2.4* |
| Cell type . | Hematopoietic . | Progenitor . | Endothelial . | |||||
|---|---|---|---|---|---|---|---|---|
| CD45 (%) . | CD3 (%) . | CD19 (%) . | CD14 (%) . | CD34 (%) . | CD133 (%) . | CD117 (%) . | CD144 (%) . | |
| ALDHlo | 98.5 ± 1.4* | 75.3 ± 5.3† | 15.4 ± 2.3* | 2.6 ± 0.8 | 1.0 ± 0.4 | 1.6 ± 0.6 | 4.7 ± 1.4 | 2.6 ± 0.4 |
| ALDHhi | 88.9 ± 5.8 | 6.2 ± 2.5 | 4.4 ± 2.1 | 12.0 ± 3.5* | 50.2 ± 1.8† | 51.7 ± 7.6† | 74.9 ± 7.5† | 8.9 ± 2.4* |
BM-derived ALDHlo cells showed increased expression of hematopoietic (CD45), and T- (CD3) and B-lymphocyte (CD19) markers. BM-derived ALDHhi cells showed increased expression of primitive progenitor (CD34, CD133, CD117), monocytic (CD14), and endothelial cell (CD144) markers. All cell-surface markers were assessed by FACS, n = 4-6.
P < .05.
P < .01.