Genotype analysis of Mll5+/− intercross progeny*
| Mouse group . | No. of mice . | No. of mice observed per genotype . | χ2 . | P . | ||
|---|---|---|---|---|---|---|
| +/+ . | −/+ . | −/ − . | ||||
| E16.5 | 87 | 20 | 45 | 22 | 0.195† | .91 |
| Male‡ | 669 | 216 | 345 | 108 | ||
| Female‡ | 601 | 181 | 326 | 94 | 3.7‡ | .48 |
| Total (at weaning) | 1270 | 397 | 671 | 202 | 64.0† | 1.29 × 10−14 |
| Mouse group . | No. of mice . | No. of mice observed per genotype . | χ2 . | P . | ||
|---|---|---|---|---|---|---|
| +/+ . | −/+ . | −/ − . | ||||
| E16.5 | 87 | 20 | 45 | 22 | 0.195† | .91 |
| Male‡ | 669 | 216 | 345 | 108 | ||
| Female‡ | 601 | 181 | 326 | 94 | 3.7‡ | .48 |
| Total (at weaning) | 1270 | 397 | 671 | 202 | 64.0† | 1.29 × 10−14 |
Late embryos (E16.5) or mice at weaning (3-4 weeks after birth) resulting from intercrosses between heterozygous (+/−) mice were genotyped, and χ2 tests were used to evaluate the fitting of the observed distribution.
Distribution with the expected Mendelian ratio of 1:2:1 (+/+, +/−, −/−)(df=2).
‡Distribution between male and female mice at weaning age(df = 4).