Selected baseline parameters of control, IDA, ACD and ACD/IDA rats
| . | Control . | IDA . | ACD . | ACD/IDA . |
|---|---|---|---|---|
| N | 6 | 7 | 7 | 6 |
| Hb, g/dL | 15.1 ± 0.23 | 12,7 ± 0.8* | 10.4 ± 2.2†‡ | 8.7 ± 1.6†‡ |
| WBC, ×103/μL | 6.0 ± 0.6 | 6.8 ± 0.7 | 30.0 ± 15.0* | 35.0 ± 16.0† |
| Fe, μmol/L | 266.9 ± 57.1 | 145.7 ± 70.5* | 68.4 ± 46.8† | 38.2 ± 24.4†‡ |
| EPO, pg/mL | 0.0 ± 0.0 | 81.7 ± 104.3† | 0.0 ± 0.0 | 321.6 ± 285.1*‡§ |
| . | Control . | IDA . | ACD . | ACD/IDA . |
|---|---|---|---|---|
| N | 6 | 7 | 7 | 6 |
| Hb, g/dL | 15.1 ± 0.23 | 12,7 ± 0.8* | 10.4 ± 2.2†‡ | 8.7 ± 1.6†‡ |
| WBC, ×103/μL | 6.0 ± 0.6 | 6.8 ± 0.7 | 30.0 ± 15.0* | 35.0 ± 16.0† |
| Fe, μmol/L | 266.9 ± 57.1 | 145.7 ± 70.5* | 68.4 ± 46.8† | 38.2 ± 24.4†‡ |
| EPO, pg/mL | 0.0 ± 0.0 | 81.7 ± 104.3† | 0.0 ± 0.0 | 321.6 ± 285.1*‡§ |
Calculations for statistical differences between the various groups were carried out by Anova analysis and Bonferroni correction for multiple tests. Data are shown as means ± SD in each group.
Hb indicates hemoglobin; WBC, white blood cell count; Fe, serum iron; and EPO, serum erythropoietin.
P < .05 when comparing control animals with IDA, ACD or ACD/IDA, respectively.
P < .001 when comparing control animals with IDA, ACD or ACD/IDA, respectively.
P < .05 when comparing IDA with ACD or ACD/IDA, respectively.
P < .05 when comparing ACD with ACD/IDA.